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8 articles for Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
16876403 Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure. 25-AUG-2006 08-DEC-2012
11311066 Design, synthesis, and discovery of a novel CCR1 antagonist. 20-APR-2001 10-NOV-2009
10602690 Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397). 24-JAN-2000 10-NOV-2009
10612590 Synthesis and biological activities of NB-506 analogues: Effects of the positions of two hydroxyl groups at the indole rings. 13-JAN-2000 10-NOV-2009
11150173 A potent, long-acting, orally active (2R)-2-[(1R)-3, 3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide: novel muscarinic M(3) receptor antagonist with high selectivity for M(3) over M(2) receptors. 18-JAN-2001 10-NOV-2009
12798328 Muscarinic M(3) receptor antagonists with (2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxyphenylacetamide Structures. Part 2. 11-JUN-2003 10-NOV-2009
10450976 Stereoselective synthesis of a new muscarinic M3 receptor antagonist, J-104129. 24-SEP-1999 10-NOV-2009
15006391 Structure-activity relationships of a novel class of endothelin receptor selective antagonists; 6-carboxy-2-isopropylamino-5,7-diarylcyclopenteno[1,2-b]pyridines. 09-MAR-2004 10-NOV-2009