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14 articles for Centre de Recherches


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
18061446 A new series of neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase. 21-JAN-2008 14-DEC-2012
16451062 Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors. 02-FEB-2006 05-DEC-2012
14521414 The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione analogues. 02-OCT-2003 30-NOV-2012
21441027 Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series. 04-APR-2011 02-DEC-2011
20079636 Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators. 15-FEB-2010 01-SEP-2010
18947994 The discovery of equipotent PPARalpha/gamma dual activators. 13-NOV-2008 11-JAN-2010
17937987 Synthesis and structure-activity relationships of thieno[2,3-b]pyrroles as antagonists of the GnRH receptor. 06-NOV-2007 11-NOV-2009
18060776 Design, synthesis and evaluation of trifluoromethane sulfonamide derivatives as new potent and selective peroxisome proliferator-activated receptor alpha agonists. 21-JAN-2008 11-NOV-2009
18313293 Neutral 5-substituted 4-indazolylaminoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase. 17-MAR-2008 11-NOV-2009
8289184 Conformational analysis of 5-lipoxygenase inhibitors: role of the substituents in chiral recognition and on the active conformations of the (methoxyalkyl)thiazole and methoxytetrahydropyran series. 22-FEB-1994 10-NOV-2009
16516473 Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: synthesis and structure-activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors. 03-APR-2006 10-NOV-2009
10579851 New alpha-substituted succinate-based hydroxamic acids as TNFalpha convertase inhibitors. 17-DEC-1999 10-NOV-2009
14521415 The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues. 02-OCT-2003 10-NOV-2009
16203139 New heterocyclic analogues of 4-(2-chloro-5-methoxyanilino)quinazolines as potent and selective c-Src kinase inhibitors. 01-NOV-2005 10-NOV-2009