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16 articles for Columbia University


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
28011205 Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation. 01-FEB-2017 05-SEP-2018
26231156 Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility. 14-OCT-2015 12-DEC-2016
23313637 Synthesis of quinoline derivatives: discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's disease. 26-FEB-2013 24-SEP-2013
23237835 Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors. 31-DEC-2012 24-SEP-2013
18434147 Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase. 05-MAY-2008 16-DEC-2012
18024113 Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation. 09-JAN-2008 15-DEC-2012
22079754 Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase. 30-DEC-2011 22-JUL-2012
17221184 Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates. XX-XXX-2007 11-JUN-2012
19101476 The importance of odorant conformation to the binding and activation of a representative olfactory receptor. 22-DEC-2008 16-AUG-2011
20529687 Synthesis and in vivo evaluation of [11C]MPTQ: a potential PET tracer for alpha2A-adrenergic receptors. 09-JUN-2010 20-NOV-2010
19303288 Discovery of potent non-urea inhibitors of soluble epoxide hydrolase. 03-APR-2009 11-JAN-2010
19243939 Potent inhibitors of Huntingtin protein aggregation in a cell-based assay. 09-MAR-2009 11-JAN-2010
19136257 Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation. 16-FEB-2009 11-JAN-2010
10757731 Two new prenylated 3-benzoxepin derivatives as cyclooxygenase inhibitors from Perilla frutescens var. acuta. 22-MAY-2000 11-JAN-2010
12190325 Ginkgolide derivatives for photolabeling studies: preparation and pharmacological evaluation. 22-AUG-2002 10-NOV-2009
12570381 Preparation of 7-substituted ginkgolide derivatives: potent platelet activating factor (PAF) receptor antagonists. 06-FEB-2003 10-NOV-2009