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35 articles for East China University of Science and Technology


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
27396490 Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes. 28-JUL-2016 18-JUL-2018
US9670213 Pteridine ketone derivative and applications thereof as EGFR, BLK, and FLT3 inhibitor 06-JUN-2017 07-JUL-2018
27552582 Development of Multifunctional Pyrimidinylthiourea Derivatives as Potential Anti-Alzheimer Agents. 22-SEP-2016 05-JUL-2018
27139780 Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN). 26-MAY-2016 09-OCT-2017
26999509 Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections. 15-APR-2016 15-SEP-2017
27220723 Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1,3-benzoazole derivatives bearing amide units. 09-JUN-2016 14-SEP-2017
22545939 Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors. XX-AUG-2013 14-AUG-2017
22524676 The efficient expression of human fibroblast collagenase in Escherichia coli and the discovery of flavonoid inhibitors. XX-AUG-2013 14-AUG-2017
26972919 Design and synthesis of thiourea derivatives with sulfur-containing heterocyclic scaffolds as potential tyrosinase inhibitors. 28-MAR-2016 10-JUL-2017
26337021 Discovery and SAR study of 3-(tert-butyl)-4-hydroxyphenyl benzoate and benzamide derivatives as novel farnesoid X receptor (FXR) antagonists. 24-9 -2015 30-NOV-2016
23664215 Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening. 20-MAY-2013 25-DEC-2014
22083916 Synthesis of (glycopyranosyl-triazolyl)-purines and their inhibitory activities against protein tyrosine phosphatase 1B (PTP1B). XX-NOV-2011 03-DEC-2014
21111404 Preparation of triazole-linked glycosylated ??????-ketocarboxylic acid derivatives as new PTP1B inhibitors. 03-JAN-2011 12-NOV-2014
24513188 Discovery and SAR study of hydroxyacetophenone derivatives as potent, non-steroidal farnesoid X receptor (FXR) antagonists. 24-FEB-2014 25-JUL-2014
23770449 Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs). 22-JUL-2013 13-APR-2014
23434140 Substituted indolin-2-ones as p90 ribosomal S6 protein kinase 2 (RSK2) inhibitors: Molecular docking simulation and structure-activity relationship analysis. 18-MAR-2013 24-SEP-2013
23429054 Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship. 09-APR-2013 24-SEP-2013
23466235 Discovery of non-peptide inhibitors of Plasmepsin II by structure-based virtual screening. 18-MAR-2013 24-SEP-2013
23122522 Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors. 26-NOV-2012 17-MAY-2013
23040732 Discovery of new non-steroidal FXR ligands via a virtual screening workflow based on Phase shape and induced fit docking. 22-OCT-2012 17-MAY-2013
22647217 Discovery and structure-activity analysis of selective estrogen receptor modulators via similarity-based virtual screening. 30-JUL-2012 08-FEB-2013
22595177 Discovery of novel EGFR tyrosine kinase inhibitors by structure-based virtual screening. 29-MAY-2012 07-FEB-2013
22658537 Natural products as a gold mine for selective matrix metalloproteinases inhibitors. 15-JUN-2012 07-FEB-2013
20553023 Discovery of potent ligands for estrogen receptor beta by structure-based virtual screening. 29-JUL-2010 31-DEC-2012
22309911 Synthesis and biological evaluation of quinazoline and quinoline bearing 2,2,6,6-tetramethylpiperidine-N-oxyl as potential epidermal growth factor receptor(EGFR) tyrosine kinase inhibitors and EPR bio-probe agents. 20-FEB-2012 22-JUL-2012
22182581 Synthesis and biological evaluation of 4-[3-chloro-4-(3-fluorobenzyloxy)anilino]-6-(3-substituted-phenoxy)pyrimidines as dual EGFR/ErbB-2 kinase inhibitors. 16-JAN-2012 22-JUL-2012
21615130 Design and synthesis of small molecule RhoA inhibitors: a new promising therapy for cardiovascular diseases? 07-JUL-2011 23-MAR-2012
21745700 Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: novel construction of PTP1B inhibitors on a sugar scaffold. 31-AUG-2011 23-MAR-2012
21665482 Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids. 24-JUN-2011 23-MAR-2012
21488662 SHAFTS: a hybrid approach for 3D molecular similarity calculation. 2. Prospective case study in the discovery of diverse p90 ribosomal S6 protein kinase 2 inhibitors to suppress cell migration. 19-MAY-2011 04-DEC-2011
21269829 Identification of small molecular inhibitors for Ero1p by structure-based virtual screening. 07-FEB-2011 23-AUG-2011
21251827 A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides. 07-FEB-2011 23-AUG-2011
20800322 Synthesis, biological assay in vitro and molecular docking studies of new imidazopyrazinone derivatives as potential dipeptidyl peptidase IV inhibitors. 11-OCT-2010 14-JUN-2011
20537438 Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods. 14-JUN-2010 19-MAR-2011
19691347 Discovering potent small molecule inhibitors of cyclophilin A using de novo drug design approach. 03-SEP-2009 26-AUG-2010