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21 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28105273 3 Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLAEBI University of Strathclyde
27933945 55 Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLAEBI Astex Pharmaceuticals
27078579 2 Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors.EBI ShanghaiTech University
27167608 25 Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.EBI Astex Pharmaceuticals
26927682 21 Discovery of Potent and Orally Active Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors as a Potential Therapy for Diabetic Macular Edema.EBI Chinese Academy of Sciences
26479945 15 Discovery of a Novel Series of Imidazo[1,2-a]pyrimidine Derivatives as Potent and Orally Bioavailable Lipoprotein-Associated Phospholipase A2 Inhibitors.EBI Chinese Academy of Sciences
23575276 15 Triazole derivatives: a series of Darapladib analogues as orally active Lp-PLA2 inhibitors.EBI Chinese Academy of Sciences
23333209 62 Amides of 4-hydroxy-8-methanesulfonylamino-quinoline-2-carboxylic acid as zinc-dependent inhibitors of Lp-PLA2.EBI ActivX Biosciences, Inc.
18657971 14 Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling.EBI The Scripps Research Institute
22217870 51 Amides of xanthurenic acid as zinc-dependent inhibitors of Lp-PLA(2).EBI ActivX Biosciences, Inc.
16919943 4 Potent inhibitors of lipoprotein-associated phospholipase A(2): benzaldehyde O-heterocycle-4-carbonyloxime.EBI National Research Laboratory of Lipid Metabolism and Atherosclerosis
15713421 9 (E)-Phenyl- and -heteroaryl-substituted O-benzoyl-(or acyl)oximes as lipoprotein-associated phospholipase A2 inhibitors.EBI National Research Laboratory of Lipid Metabolism and Atherosclerosis
12643913 55 The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2.EBI GlaxoSmithKline
12182870 54 The discovery of SB-435495. A potent, orally active inhibitor of lipoprotein-associated phospholipase A(2) for evaluation in man.EBI GlaxoSmithKline
11738571 36 Potent, orally active inhibitors of lipoprotein-associated phospholipase A(2): 1-(biphenylmethylamidoalkyl)-pyrimidones.EBI GlaxoSmithKline
11459662 41 1-(Arylpiperazinylamidoalkyl)-pyrimidones: orally active inhibitors of lipoprotein-associated phospholipase A(2).EBI GlaxoSmithKline
11266173 1 The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2.EBI GlaxoSmithKline Pharmaceuticals
11086729 51 N-1 substituted pyrimidin-4-ones: novel, orally active inhibitors of lipoprotein-associated phospholipase A2.EBI SmithKline Beecham Pharmaceuticals
10714508 41 2-(Alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2.EBI SmithKline Beecham Pharmaceuticals
9341913 28 Structure-activity relationships of (4-acylpyrrol-2-yl)alkanoic acids as inhibitors of the cytosolic phospholipase A2: variation of the substituents in positions 1, 3, and 5.EBI Ludwig-Maximilians-University
9276015 41 Synthesis, biological evaluation, and structure-activity relationships of 3-acylindole-2-carboxylic acids as inhibitors of the cytosolic phospholipase A2.EBI Ludwig-Maximilians-University