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26 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28300404 4 Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.EBI Janssen R&D LLC
25078315 7 Discovery of highly potent TNFa inhibitors using virtual screen.EBI Peking University
24974349 20 Prediction of anti-tumor chemical probes of a traditional Chinese medicine formula by HPLC fingerprinting combined with molecular docking.EBI The Second People's Hospital of Fujian Provinc
18075579 9 Reaching for high-hanging fruit in drug discovery at protein-protein interfaces.EBI University of California at San Francisco
10508435 61 Substituted isoquinolines and quinazolines as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha.EBI University of California
15953722 56 Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.EBI Pfizer Global Research and Development
8765505 26 Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity.EBI Celgene Corporation
8759624 1 Potent inhibition of tumor necrosis factor-alpha production by tetrafluorothalidomide and tetrafluorophthalimides.EBI Institute of Technology
8568809 34 Substituted xanthines, pteridinediones, and related compounds as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha.EBI University of California
24943831 8 Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reaction.BDB University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain)
24707965 33 A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1.BDB Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States
19827831 83 Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes.BDB Novartis
19398200 45 Optimization of benzimidazole series as opioid receptor-like 1 (ORL1) antagonists: SAR study directed toward improvement of selectivity over hERG activity.BDB Banyu Pharmaceutical Co.
17500511 19 Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists.BDB Johnson & Johnson Pharmaceutical
18393489 11 Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine a.BDB University of British Columbia
15895686 3 Glutamylsulfamoyladenosine and pyroglutamylsulfamoyladenosine are competitive inhibitors of E. coli glutamyl-tRNA synthetase.BDB CREFSIP
16392822 87 2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV.BDB National Health Research Institutes
 8 INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C(2) SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE.BDB NCI-FCRDC