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31 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
 58 Non-glycosidic/non-aminoalkyl-substituted indolocarbazoles as inhibitors of protein kinase CEBI TBA
11451670 11 Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis.BDB The Scripps Research Institute
10322126 60 Structure-based discovery and in-parallel optimization of novel competitive inhibitors of thymidylate synthase.BDB Northwestern University
16789731 3 Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.BDB University of Michigan
16759082 9 Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.BDB University of Michigan
19072652 64 Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.BDB Medical University of South Carolina
17614275 16 Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.BDB Lilly Research Laboratories
11567092 4 Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.BDB GSK
17049867 5 Synthesis of beta-ketophosphonate analogs of glutamyl and glutaminyl adenylate, and selective inhibition of the corresponding bacterial aminoacyl-tRNA synthetases.BDB CREFSIP
17444623 29 Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.BDB Schering-Plough Research Institute
17120228 14 Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.BDB The Procter & Gamble Pharmaceuticals
17696512 50 Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2' Ligands in Pseudosymmetric Dipeptide Isosteres.BDB University of Massachusetts Medical School
16495061 8 Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent.BDB Johnson & Johnson Pharmaceutical
16982192 8 Arylsulfonamides: a study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors.BDB GlaxoSmithKline
16279769 28 Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives.BDB Universita degli Studi di Roma La Sapienza
15689148 19 Bis-huperzine B: highly potent and selective acetylcholinesterase inhibitors.BDB Shanghai Institute of Materia Medica
15985434 18 Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives.BDB Chinese Academy of Sciences
15664516 21 Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases.BDB University of Dundee
16023344 120 Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors.BDB Merck Frosst Canada & Co.
12852749 11 First dual aromatase-steroid sulfatase inhibitors.BDB University of Bath
8667367 28 Synthesis and structure-activity relationships of 6-substituted androst-4-ene analogs as aromatase inhibitors.BDB Tohoku College of Pharmacy
15911319 10 Synthesis and characterization of azole isoflavone inhibitors of aromatase.BDB Ohio State University