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311 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28658574 124 3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold To Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII.EBI Universit£ degli Studi di Firenze
28272885 126 Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action.EBI Universit£ degli Studi di Firenze
28256371 83 Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects.EBI University of Wollongong
28161252 64 Synthesis and biological evaluation of cyclic imides incorporating benzenesulfonamide moieties as carbonic anhydrase I, II, IV and IX inhibitors.EBI King Saud University
25432060 92 Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties.EBI Atat£rk University
28075587 102 Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis.EBI University of Florence
27823879 88 New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs.EBI Maastricht University Medical Centre
1635066 17 Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity.EBI Istituto Chimico Internazionale Dr. G. Rende
3735316 8 N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure.EBI TBA
28065499 84 Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors.EBI Kurukshetra University
28024887 52 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations.EBI Riga Technical University
27939347 52 Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.EBI Universit£ degli Studi di Firenze
27933963 60 Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations.EBI Universit£ degli Studi di Firenze
27144971 60 PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas.EBI Temple University School of Pharmacy
27290692 18 N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition.EBI Universit£ degli Studi di Firenze
27172398 20 An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C.EBI Griffith University
27316543 24 Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Firenze
27234893 36 Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.EBI Cairo University
27166574 52 Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII.EBI Kurukshetra University
27137360 100 Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII.EBI Kurukshetra University
26805033 426 Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.EBI Uppsala University
26875933 72 Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma.EBI DAIS
26840366 72 Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII.EBI Egyptian Russian University
26741028 100 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.EBI Universit£ de Reims Champagne-Ardenne
26810836 28 Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111.EBI University of Florida College of Medicine
26810710 116 A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms.EBI University of Chieti-Pescara
26688270 104 Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins.EBI Universit£ degli Studi di Firenze
26803577 92 Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII.EBI Harran University
26520662 45 Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives.EBI Balikesir University
26497049 110 Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors.EBI Sapienza University of Rome
26498394 105 Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters.EBI Universit£ degli Studi di Firenze
26408817 69 Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII.EBI Egyptian Russian University
26432607 60 Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII.EBI Universit£ degli Studi di Firenze
26422787 68 Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII.EBI Dumlupinar University
26347950 32 Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.EBI Griffith University
26319622 12 Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents.EBI Universit£ degli Studi di Firenze
26276436 45 Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms.EBI Universit£ degli Studi di Messina
26233435 76 Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity.EBI University of Cagliari
26264840 104 Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies.EBI University of Chieti-Pescara
26160114 101 Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms.EBI Saint Petersburg State University
26191373 52 Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series.EBI Institute of Biomolecules Max Mousseron (IBMM)
26233796 68 Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties.EBI University of Cagliari
26203869 18 Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates.EBI University of Florida
26105196 52 Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.EBI Kurukshetra University
26073006 56 New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII.EBI University of Cagliari
26048024 84 Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.EBI Jazan University
26088336 96 5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII.EBI University of Belgrade
25921266 48 New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors.EBI Siedlce University of Natural Sciences and Humanities
26007302 56 New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies.EBI University of Chieti-Pescara
25875209 60 6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.EBI Latvian Institute of Organic Synthesis
25913118 95 Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII.EBI Harran University
25912674 52 Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives.EBI Cairo University
25553540 6 1,3,4-Thiadiazoles: a potent multi targeted pharmacological scaffold.EBI University of Mississippi
25846066 88 Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.EBI Universit£ degli Studi di Firenze
25766630 100 A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects.EBI Universit£ degli Studi di Firenze
25757603 79 New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity.EBI Siedlce University of Natural Sciences and Humanities
25753329 56 Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action.EBI Latvian Institute of Organic Synthesis
25147616 92 Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry.EBI Universit£ di Sassari
25050167 40 Carbonic anhydrase inhibitors: design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives.EBI Bharati Vidyapeeth's College of Pharmacy
25027802 56 Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies.EBI Sapienza University of Rome
25022971 124 Furazan and furoxan sulfonamides are stronga-carbonic anhydrase inhibitors and potential antiglaucoma agents.EBI Universit£ degli Studi di Torino
25019479 96 Cyclic tertiary sulfamates: selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives.EBI Sapienza University of Rome
24948563 44 Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors.EBI University of Perugia
25468040 77 Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.EBI TBA
25456084 100 4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII.EBI Kurukshetra University
25442309 120 Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds.EBI King Saud University
25438758 44 Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: towards new carbonic anhydrase glycoinhibitors.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
25358084 143 Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.EBI Vilnius University
25358036 64 A class of 4-sulfamoylphenyl-┐-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.EBI Universit£ degli Studi di Firenze
25310626 80 Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.EBI Universit£ degli Studi di Firenze
25267005 70 Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones.EBI Universit£ degli Studi di Firenze
25255434 84 Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling.EBI King Saud University
25254302 44 Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates.EBI Griffith University
25245672 5 Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis,▀-glucuronidase inhibition activity, crystal structure, and POM analyses.EBI King Saud University
25156300 48 Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.EBI Universidad Nacional de La Plata
24878360 76 Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties.EBI King Saud University
24871996 124 Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.EBI Medical University of Gdansk
24813742 98 Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors.EBI Universit£ degli Studi
24713308 48 Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity.EBI Siedlce University of Natural Sciences and Humanities
24589511 60 Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties.EBI University of Cagliari
24689792 54 Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.EBI Griffith University
24650641 110 Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII.EBI Universit£ degli Studi 'Aldo Moro' di Bari
23664215 45 Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening.EBI East China University of Science and Technology
23647428 84 Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo.EBI Universit£ degli Studi di Firenze
23490152 15 Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition.EBI University of Florida
23429054 48 Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship.EBI East China University of Science and Technology
23352754 28 o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII.EBI Istanbul University
23290254 92 Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII.EBI Salman Bin Abdulaziz University
23206986 259 QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII.EBI Romanian Academy
23199483 25 Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
23168081 72 New selective carbonic anhydrase IX inhibitors: synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides.EBI University of Lille
23098607 2 Carbonic anhydrase IX as a target for metastatic disease.EBI University of Manchester
23018095 36 Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Pisa
23010455 108 Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.EBI Universidad Nacional de La Plata
22974493 13 Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity.EBI Agri Ibrahim Cecen University
22892213 168 Natural product coumarins that inhibit human carbonic anhydrases.EBI Griffith University
22705188 73 Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: new selective tumor-associated carbonic anhydrase inhibitors.EBI Superacide et Chimie des syst£mes£ team-Universit£ de Poitiers
22668600 200 Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV.EBI Universit£ degli Studi di Firenze
23265898 20 Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.EBI Universit£ degli Studi di Firenze
23241068 84 Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases.EBI Latvian Association of Human Genetics
22910138 96 Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.EBI TBA
23067387 105 Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.EBI Universit£ di Pisa
22894736 99 Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment.EBI The Hebrew University of Jerusalem
22775345 74 Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.EBI Istituto di Biostrutture e Bioimmagini-CNR
22621623 44 Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts.EBI University of Manchester
22901388 76 Inhibition ofa-class cytosolic human carbonic anhydrases I, II, IX and XII, andß-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors.EBI Universit£ di Sassari
22721713 200 Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
22443141 115 Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors.EBI Universit£ di Messina
22276570 112 Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.EBI Universit£ degli Studi di Firenze
22487176 109 Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.EBI Universit£ degli Studi di Cagliari
21211980 47 Characterization and anions inhibition studies of ana-carbonic anhydrase from the teleost fish Dicentrarchus labrax.EBI Ondokuz Mayis University
20580561 33 Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity.EBI Instituto Superior T£cnico
20674354 79 Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.EBI Universit£ degli Studi di Firenze
20605094 91 Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.EBI University of Florida
20598552 24 Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.EBI University of Florida
20478708 28 New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors.EBI LNEG
20472429 80 Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.EBI Istituto di Biostrutture e Bioimmagini-CNR
20201556 174 Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases.EBI Griffith University
20185318 132 Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.EBI Universit£ degli Studi di Firenze
19911821 273 Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.EBI Universita degli Studi di Firenze
20028100 78 The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Firenze
19827837 52 S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.EBI Griffith University
19398204 44 Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides.EBI Universit£ di Messina
19286378 75 Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties.EBI Griffith University
19186056 60 A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.EBI Universit£ degli Studi di Firenze
18513964 45 Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes.EBI Universit£ degli Studi di Firenze
18359629 84 Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.EBI Istituto di Biostrutture e Bioimmagini-CNR
18042384 60 Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
18307288 70 Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.EBI Griffith University
17475500 130 Carbonic anhydrases as targets for medicinal chemistry.EBI Universit£ degli Studi di Firenze
17681760 21 Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.EBI Griffith University
17376683 63 Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
17314045 11 Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.EBI Universit£ degli Studi di Firenze
17276072 95 Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates.EBI Universit£ di Pisa
17228881 141 Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.EBI Kochi Medical School
16290146 30 Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II"selective" inhibitor celecoxib.EBI Istituto di Biostrutture e Bioimmagini-CNR
16203142 55 Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.EBI Universit£ degli Studi di Firenze
16220969 219 Designed multiple ligands. An emerging drug discovery paradigm.EBI Organon Laboratories
15664816 65 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.EBI Universit£ degli Studi di Firenze
15664814 55 Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.EBI Universit£ degli Studi di Firenze
15603956 63 Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.EBI Harran University
16039848 93 Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.EBI Kochi Medical School
15905091 134 Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.EBI Universit£ degli Studi di Firenze
15546717 130 Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.EBI Pennsylvania State University
15501039 51 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.EBI Universit£ degli Studi di Firenze
15501038 68 Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.EBI Universit£ degli Studi di Firenze
15454239 74 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.EBI Universit£ degli Studi di Firenze
12747791 91 Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors.EBI University of Montpellier
15012984 192 Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.EBI Slovak Academy of Sciences
15081039 68 Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.EBI Universit£ degli Studi di Firenze
15203157 68 Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.EBI University of Tampere
15149691 32 Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.EBI Laxmi Fumigation and Pest Control (P)
14684333 9 Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase.EBI Universit£ degli Studi di Firenze
14684331 24 Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.EBI Universit£ degli Studi di Firenze
12643899 127 Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.EBI Universit£ degli Studi di Firenze
22377674 80 Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII.EBI Universit£ degli Studi di Firenze
22370338 183 Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases.EBI Griffith University
22365761 144 New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.EBI Universit£ degli Studi di Firenze
22077347 44 Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
22137345 36 5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors.EBI Universit£ degli Studi di Firenze
22041171 44 Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors.EBI Universit£ di Messina
21852133 68 Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.EBI University of Alberta
21851094 92 Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.EBI Griffith University
21821413 65 Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
21820216 75 Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives.EBI Medical University of Gdansk
21515057 153 Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.EBI Universit£ degli Studi di Firenze
21723123 48 N-ß-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.EBI Universidad Nacional de La Plata
21470859 52 Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
21549597 71 Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.EBI U.O. Oculistica Az. USL 3
21361354 112 Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.EBI Universita` degli Studi di Firenze
21314129 76 Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors.EBI Griffith University
21282059 48 Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site.EBI University of Calgary
21067924 88 7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range.EBI Università degli Studi di Firenze
20880712 69 Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors.EBI University of Lille
20554082 76 Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.EBI Medical University of Gdansk
20590092 273 Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.EBI Universita degli Studi di Firenze
20202722 138 Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides.EBI Medical University of Gdansk
19751975 6 The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors.EBI Universita degli Studi di Firenze
19615903 6 In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives.EBI Institute of Pharmaceutical Sciences
19527930 53 The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.EBI University of Tampere and Tampere University Hospital
19097911 41 Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors.EBI University of Namur
19053764 101 Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates.EBI Instituto Superior Técnico
18348513 19 Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs.EBI University of Namur
18295485 75 Carbonic anhydrase inhibitors: the very weak inhibitors dithiothreitol, beta-mercaptoethanol, tris(carboxyethyl)phosphine and threitol interfere with the binding of sulfonamides to isozymes II and IX.EBI Universita degli Studi di Firenze
17822907 90 Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity.EBI Assiut University
17257840 20 Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions.EBI Università degli Studi di Firenze
16809036 100 Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.EBI Medical University of Gdansk
16759856 9 N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors.EBI Università degli Studi di Firenze
16168653 100 Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.EBI Università degli Studi di Firenze
16165351 45 Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides.EBI Università degli Studi di Firenze
16033263 51 Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.EBI Università degli Studi di Firenze
15908204 116 Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.EBI Ospedale San Lazzaro
15908201 51 Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxic tumors.EBI Università degli Studi di Firenze
15837325 69 Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.EBI Ospedale San Lazzaro
15837323 66 Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.EBI University of Bucharest
15780637 3 Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.EBI University of Naples 'Federico II'
15780631 55 Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with complex fluorides, chlorides and cyanides.EBI Università degli Studi di Firenze
15745821 21 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates.EBI University of Montpellier
15664815 45 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates.EBI Università degli Studi di Firenze
15501037 27 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet.EBI Università degli Studi di Milano
14640555 96 Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.EBI University of Montpellier
26796953 60 Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII.EBI Universit£ di Pisa
26795114 72 Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action.EBI National University of La Plata
26682703 30 Fluorescent sulfonamide carbonic anhydrase inhibitors incorporating 1,2,3-triazole moieties: Kinetic and X-ray crystallographic studies.EBI Universit£ degli Studi di Firenze
24589484 92 4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII.EBI Kurukshetra University
24560739 124 Design, synthesis and evaluation of N-substituted saccharin derivatives as selective inhibitors of tumor-associated carbonic anhydrase XII.EBI Sapienza University of Rome
24518190 88 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII.EBI Latvian Institute of Organic Synthesis
24560737 88 Benzenesulfonamide bearing 1,2,4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII.EBI Kurukshetra University
24507918 68 Substituted benzene sulfonamides incorporating 1,3,5-triazinyl moieties potently inhibit human carbonic anhydrases II, IX and XII.EBI Shri G.S. Institute of Technology and Science
24513186 52 Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII.EBI Latvian Institute of Organic Synthesis
24513184 84 Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties.EBI Birla Institute of Technology
24291567 154 Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.EBI Medical University of Gdansk
24300919 55 Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.EBI Universit£ degli Studi di Firenze
24287559 36 Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors.EBI Universit£ di Messina
24200125 135 A prodrug approach toward cancer-related carbonic anhydrase inhibition.EBI Griffith University
24189056 64 Salen and tetrahydrosalen derivatives act as effective inhibitors of the tumor-associated carbonic anhydrase XII--a new scaffold for designing isoform-selective inhibitors.EBI Sapienza University of Rome
24128000 60 Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates.EBI Ecole Nationale Sup£rieure de Chimie de Montpellier
24103430 78 Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties.EBI Universit£ degli Studi di Firenze
24090602 21 Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.EBI University of Florida
24012377 22 Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition.EBI Universit£ degli Studi di Firenze
24095761 72 Carbonic anhydrase inhibitors. Synthesis of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives and their inhibition of the human cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII.EBI Medical University of Gdansk
23993330 10 Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII.EBI University of Florida
23965175 105 Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety.EBI Birla Institute of Technology
23859774 64 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.EBI Latvian Association of Human Genetics
23842519 116 Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides.EBI Bezmialem Vakif University
23827177 33 Design and synthesis of novel 4-(4-oxo-2-arylthiazolidin-3-yl)benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity.EBI Manipal College of Pharmaceutical Sciences
23777898 40 Sulfonamides containing coumarin moieties selectively and potently inhibit carbonic anhydrases II and IX: design, synthesis, inhibitory activity and 3D-QSAR analysis.EBI Nanjing University
23769167 85 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.EBI Universit£ degli Studi di Firenze
23706268 4 Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.EBI University of W£rzburg
23623256 38 Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine.EBI Atat£rk University
30193219 114 Discovery of new 2, 5-disubstituted 1,3-selenazoles as selective human carbonic anhydrase IX inhibitors with potent anti-tumor activity.EBI Department of University of Florence
30071407 76 Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies.EBI Egyptian Russian University
30015076 84 Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, inávitro and inávivo appraisal.EBI University of Delhi
30344915 45 Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides.EBI University of Cagliari
30344913 24 Famotidine, an Antiulcer Agent, Strongly Inhibits EBI University of Florence
30433782 88 4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides Selectively Target the Tumor-Associated Carbonic Anhydrase Isoforms IX and XII Showing Hypoxia-Enhanced Antiproliferative Profiles.EBI Universit£ degli Studi di Firenze
29962205 100 Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX.EBI University of Florence
29685656 8 Synthesis, structure and bioactivity of primary sulfamate-containing natural products.EBI Griffith University
29571155 124 Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors.EBI Kurukshetra University
30258546 56 Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines.EBI University of Florence
28947945 72 Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors.EBI University of Florence
28947941 44 Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.EBI University of Sassari
28802125 92 Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.EBI Kafrelsheikh University
29746127 195 Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.EBI Ege University Bornova
29305297 480 Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors.EBI Vilnius University
30006175 644 Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases.EBI Vilnius University
29909339 84 Design and synthesis of novel benzenesulfonamide containing 1,2,3-triazoles as potent human carbonic anhydrase isoforms I, II, IV and IX inhibitors.EBI Kurukshetra University
29852328 22 Synthesis, characterization and biological evaluation of tertiary sulfonamide derivatives of pyridyl-indole based heteroaryl chalcone as potential carbonic anhydrase IX inhibitors and anticancer agents.EBI Jamia Millia Islamia
29803994 56 Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects.EBI Universit£ degli Studi di Firenze
29684705 72 Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform.EBI Egyptian Russian University
29635168 140 2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and inávivo activity for a new class of intraocular pressure lowering agents.EBI University of Florence
30034608 52 Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors.EBI University of Cagliari
30034596 8 Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose.EBI University of Florida
29912561 40 4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors.EBI Universit£ di Pisa
29795760 90 Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology.EBI University of Florence
29407972 160 Structural investigations on coumarins leading to chromeno[4,3-c]pyrazol-4-ones and pyrano[4,3-c]pyrazol-4-ones: New scaffolds for the design of the tumor-associated carbonic anhydrase isoforms IX and XII.EBI Universit£ degli Studi di Firenze
29289880 25 Design, synthesis and biological evaluation of novel pyridine-thiazolidinone derivatives as anticancer agents: Targeting human carbonic anhydrase IX.EBI Jamia Millia Islamia
29851481 122 Discovery of ?-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.EBI University of Florence
29197732 112 Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases.EBI University of Messina
29146134 64 Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies.EBI Medical University of Gdansk
29259736 70 Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors.EBI University of Florence
29259754 76 Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases.EBI University of Florence
30017112 36 Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery.EBI Abbottabad University of Science and Technology
28835790 64 -Acylbenzenesulfonamide Dihydro-1,3,4-oxadiazole Hybrids: Seeking Selectivity toward Carbonic Anhydrase Isoforms.EBI University of Cagliari
28887000 72 Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors.EBI National Institute of Pharmaceutical Education and Research (NIPER)
28789908 64 Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties.EBI Universit£ degli Studi di Firenze
28728897 4 1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads.EBI Universita degli Studi di Firenze
28277280 43 Bortezomib inhibits mammalian carbonic anhydrases.EBI Universit£ degli Studi di Firenze
28545816 56 Novel sulfonamide-containing 2-indolinones that selectively inhibit tumor-associated alpha carbonic anhydrases.EBI Istanbul University
28522267 72 Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors.EBI Universit£ degli Studi di Firenze
28400084 68 Synthesis and biological evaluation of novel aromatic and heterocyclic bis-sulfonamide Schiff bases as carbonic anhydrase I, II, VII and IX inhibitors.EBI Adiyaman University
28334643 24 Dual-tail approach to discovery of novel carbonic anhydrase IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site.EBI Shenyang Pharmaceutical University
28302505 120 Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors.EBI Universit£ degli Studi di Firenze
29266943 8 "Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms.EBI University of Florida
29048889 7 Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX).EBI University of Florence
28389112 72 Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII.EBI Universit£ degli Studi di Firenze
29466001 208 Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design.EBI Vilnius University
28416101 60 N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII.EBI Latvian Institute of Organic Synthesis
28347633 92 Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs.EBI Universit£ degli Studi di Firenze
28453941 114 Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides.EBI Universit£ degli Studi di Messina
28259376 11 Green synthesis, inhibition studies of yeast a-glucosidase and molecular docking of pyrazolylpyridazine amines.BDB University of the Punjab
27723749 4 SF2312 is a natural phosphonate inhibitor of enolase.BDB University of Texas M. D. Anderson Cancer Center
27570878 7 A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase.BDB Utrecht University
26773755 20 Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives.BDB Indian Institute of Integrative Medicine
10945872 14 Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.BDB SmithKline Beecham Pharmaceuticals Ltd
10900230 11 Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s).BDB University of Michigan
8510008 67 Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines.BDB Eli Lilly and Company
7830490 21 SR 142801, the first potent non-peptide antagonist of the tachykinin NK3 receptor.BDB Sanofi Recherche
7815325 65 Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.BDB Duke University
3130534 3 7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist.BDB Tokushima Research Institute
2664084 17 Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein.BDB Albany Medical College
2547939 11 Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor.BDB Abbott Laboratories
2537406 2 Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells.BDB University of Arizona
19884015 17 Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties.BDB Daiichi Sankyo Co., Ltd
19900813 12 Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes.BDB Astellas Pharma Inc
19764794 60 Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.BDB Amgen Inc
18621523 10 Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064.BDB GSK
19394217 14 2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists.BDB Banyu Pharmaceutical Co.
19007201 20 Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.BDB Roche Palo Alto LLC
19175319 19 Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays (dagger).BDB Pfizer Inc
11305907 3 The vnd/NK-2 homeodomain: thermodynamics of reversible unfolding and DNA binding for wild-type and with residue replacements H52R and H52R/T56W in helix III.BDB National Institutes of Health