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20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27816515 143 Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors.EBI Merck & Co.
27727125 24 Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators.EBI Pfizer Inc
27490827 24 Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy.EBI Pfizer Inc
24900695 19 Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators.EBI Chinese Academy of Sciences
23550937 72 Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties.EBI Emory University
22795331 51 Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket.EBI Janssen Pharmaceutical Companies of Johnson & Johnson L.L.C.
24900346 90 Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.EBI TBA
26510622 2 Pharmacological Targeting of AMP-Activated Protein Kinase and Opportunities for Computer-Aided Drug Design.EBI Maastricht University
30036059 40 Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).EBI Pfizer Inc.
29620890 25 Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations.EBI GlaxoSmithKline
28345906 9 Malonylginsenosides with Potential Antidiabetic Activities from the Flower Buds of Panax ginseng.EBI Chinese Academy of Sciences
29348809 1 Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.EBI Merck Research Laboratories
29035567 38 Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase.EBI Metabasis Therapeutics Inc
29466005 25 Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK).EBI Pfizer Inc
20020776 56 In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors.BDB Vanderbilt University