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37 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26260335 14 Tight binding enantiomers of pre-clinical drug candidates.EBI Victoria University of Wellington
31484 4 Stereoelectronic factors in the binding of substrate analogues and inhibitors to purine nucleoside phosphorylase isolated from human erythrocytes.EBI TBA
22264015 29 N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.EBI Academy of Sciences of the Czech Republic
19386496 3 Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II.EBI BioCryst Pharmaceuticals Inc.
19170524 38 Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.EBI Industrial Research Limited
18778937 15 Immucillins in custom catalytic-site cavities.EBI Albert Einstein College of Medicine of Yeshiva University
17004717 22 Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activity.EBI Universit£ degli Studi di Siena
15163207 27 Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.EBI Industrial Research Limited
14613329 11 Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.EBI Industrial Research Limited
12852771 26 Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.EBI Industrial Research Limited
8478902 18 Nucleosides. 5. Synthesis of guanine and formycin B derivatives as potential inhibitors of purine nucleoside phosphorylase.EBI National Defense Medical Center
8254607 36 Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group.EBI BioCryst Pharmaceuticals, Inc.
1578487 12 Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-thienylmethyl)-4H-pyrrolo[3,2-d] pyrimidin-4-oEBI Warner-Lambert Company
1573639 17 Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues.EBI Warner-Lambert Company
3123692 5 Synthesis and evaluation of 5-amino-1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine and certain related nucleosides as inhibitors of purine nucleoside phosphorylase.EBI Nucleic Acid Research Institute
3091835 3 Inhibitors of human purine nucleoside phosphorylase. Synthesis, purine nucleoside phosphorylase inhibition, and T-cell cytotoxicity of 2,5-diaminothiazolo[5,4-d]pyrimidin-7(6H)-one and 2,5-diaminothiazolo[4,5-d]pyrimidin-7(6H)-one. Two thio isosteres of 8-aminoguanine.EBI TBA
3093681 7 Synthesis of 8-amino-3-deazaguanine via imidazole precursors. Antitumor activity and inhibition of purine nucleoside phosphorylase.EBI TBA
11959007 27 Benzimidazole-4,7-diones as inhibitors of protozoal (Toxoplasma gondii) purine nucleoside phosphorylase.EBI Universit£ Lyon I
 19 Phosphonate derivatives of N9-benzylguanine: a new class of potent purine nucleoside phosphorylase inhibitorsEBI TBA
20817362 25 Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase.EBI Instituto de Parasitología y Biomedicina López-Neyra
19620996 2 Enzymatic transition states and dynamic motion in barrier crossing.EBI Albert Einstein College of Medicine
20189401 24 Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs.EBI Tokyo University of Pharmacy and Life Sciences
20129792 10 Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.EBI Universidade Federal da Bahia
19386498 3 Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part I.EBI BioCryst Pharmaceuticals Inc.
18800772 18 A beta-fluoroamine inhibitor of purine nucleoside phosphorylase.EBI Industrial Research Limited
17544667 10 Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP.EBI Tokyo University of Pharmacy and Life Sciences
12502369 8 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.EBI Industrial Research Limited
10522701 14 Synthesis and biological evaluation of 1,1-difluoro-2-(tetrahydro-3-furanyl)ethylphosphonic acids possessing a N9-purinylmethyl functional group at the ring. a new class of inhibitors for purine nucleoside phosphorylases.EBI Tokyo University of Pharmacy & Life Science
8632418 21 Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase.EBI Burroughs Wellcome Co.
8421291 73 Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine.EBI BioCryst Pharmaceuticals, Inc.
8230137 14 9-[(Phosphonoalkyl)benzyl]guanines. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase.EBI Burroughs Wellcome Co.
8164252 18 Structure-based design of inhibitors of purine nucleoside phosphorylase. 4. A study of phosphate mimics.EBI Ciba-Geigy Corporation
7699692 14 [[(Guaninylalkyl)phosphinico]methyl]phosphonic acids. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase.EBI Burroughs Wellcome Co.