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31 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27228159 2 Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.EBI Mahidol University
26287401 39 Lanostane Triterpenes from the Tibetan Medicinal Mushroom Ganoderma leucocontextum and Their Inhibitory Effects on HMG-CoA Reductase anda-Glucosidase.EBI Chinese Academy of Sciences
25022881 1 Molecular modeling studies of atorvastatin analogues as HMGR inhibitors using 3D-QSAR, molecular docking and molecular dynamics simulations.EBI Shanghai Institute of Technology
25311563 12 Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors.EBI Instituto Polit£cnico Nacional (IPN)
23570542 48 Design and synthesis of dual-action inhibitors targeting histone deacetylases and 3-hydroxy-3-methylglutaryl coenzyme A reductase for cancer treatment.EBI National Taiwan University
 6 C-2 desmethyl seco-mevinic acids. Monocyclic HMG-CoA reductase inbibitorsEBI TBA
19879766 11 Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones.EBI Institute of Pharmaceutical Industry
15686906 34 Three-dimensional quantitative structure (3-D QSAR) activity relationship studies on imidazolyl and N-pyrrolyl heptenoates as 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) inhibitors by comparative molecular similarity indices analysis (CoMSIA).EBI National Institute of Pharmaceutical Education and Research (NIPER)
1527791 8 Synthesis and biological evaluation of dihydroeptastatin, a novel inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.EBI British Bio-technology Limited
1597859 14 Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted- pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones.EBI Warner-Lambert Company
1656041 75 Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.EBI Hoechst AG
21872367 2 Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent.EBI Central Drug Research Institute (CSIR)
20494585 27 Peptide fragmentation as an approach in modeling of an active peptide and designing a competitive inhibitory peptide for HMG-CoA reductase.EBI Institute of the Chemistry of Plant Substances
 11 Novel Acetylenic Acids from the Root Bark of Paramacrolobium caeruleum: Inhibitors of 3-Hydroxy-3-methyl-glutaryl Coenzyme A ReductaseEBI TBA
 18 Synthesis of tetrazol-1-yl analogs of HMG-COA reductase inhibitor BMS180431 (formerly BMY21950)EBI TBA
 2 Phosphinic acid inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme a reductaseEBI TBA
17574412 31 Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.EBI Pfizer Global Research & Development
17574411 15 Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.EBI Pfizer Global Research & Development
15686898 8 Molecular docking of the highly hypolipidemic agent alpha-asarone with the catalytic portion of HMG-CoA reductase.EBI Universidad Nacional Autónoma de México
11392538 2 Synthesis and biological evaluations of condensed pyridine and condensed pyrimidine-based HMG-CoA reductase inhibitors.EBI Central Research Institute
8426367 10 32-Methyl-32-oxylanosterols: dual-action inhibitors of cholesterol biosynthesis.EBI Institute
8057282 2 Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription.EBI Upjohn Laboratories
2296036 48 Synthesis and biological activity of new HMG-CoA reductase inhibitors. 1. Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids.EBI Hoechst AG
2153213 28 Synthesis and biological activity of new HMG-CoA reductase inhibitors. 2. Derivatives of 7-(1H-pyrrol-3-yl)-substituted-3,5-dihydroxyhept-6(E)-enoic (-heptanoic) acids.EBI Hoechst AG
1433193 7 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs.EBI Merck Research Laboratories
19875078 5 Discovery of potent and reversible monoacylglycerol lipase inhibitors.BDB University of California Irvine
19716475 20 Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD.BDB Burnham Institute for Medical Research
19389627 2 Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.BDB Pfizer