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28 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
12639555 10 Synthesis and anti-influenza evaluation of orally active bicyclic ether derivatives related to zanamivir.EBI Sankyo Co., Ltd.
12113810 20 Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir.EBI Sankyo Co., Ltd.
12113809 12 Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives.EBI Sankyo Co., Ltd.
22677529 3 Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: the hydrophobic side chain influences type A subtype selectivity.EBI University of Alabama at Birmingham
18694948 17 Limited inhibitory effects of oseltamivir and zanamivir on human sialidases.EBI Miyagi Cancer Center Research Institute
15214773 76 Fragment-based drug discovery.EBI Sunesis Pharmaceuticals Inc.
11000002 10 BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.EBI BioCryst Pharmaceuticals, Inc.
10602699 15 Binding constants of neuraminidase inhibitors: An investigation of the linear interaction energy method.EBI University of Southampton
9526556 18 Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.EBI Glaxo Wellcome Research and Development Limited
8126701 3 Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis.EBI Monash University
11266166 36 Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides.EBI Glaxo Wellcome Medicines Research Centre
 22 Novel inhibitors of influenza sialidases related to zanamivir. Heterocyclic replacements of the glycerol sidechainEBI TBA
 14 Structure-activity relationships of carbocyclic influenza neuraminidase inhibitorsEBI TBA
 51 Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamidesEBI TBA
 16 Novel inhibitors of influenza sialidase related to GG167 Synthesis of 4-amino and guanidino-4H-pyran-2-carboxylic acid-6-propylamides; selective inhibitors of influenza a virus sialidaseEBI TBA
22100261 12 Synthesis and biological evaluation of sialic acid derivatives containing a long hydrophobic chain at the anomeric position and their C-5 linked polymers as potent influenza virus inhibitors.EBI Saitama University
21843936 35 3D QSAR and docking study of flavone derivatives as potent inhibitors of influenza H1N1 virus neuraminidase.EBI Chinese Academy of Medical Sciences
20014777 6 Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai.EBI University of Innsbruck
15828835 6 Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.EBI GlaxoSmithKline Medicines Research Centre
15582424 6 Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.EBI Abbott Laboratories
11312919 22 Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores.EBI Abbott Laboratories
10395473 19 Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent.EBI University of Alabama at Birmingham
16621549 40 Novel 5-azaindole factor VIIa inhibitors.BDB Celera
14561087 27 Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).BDB Boehringer Ingelheim Pharmaceuticals Inc.
11896401 3 Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.BDB Boehringer Ingelheim Pharmaceuticals Inc.
15857116 5 1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyanopyrazin-2-yl)ureas [correction of cyanopyrazi] as potent and selective inhibitors of Chk1 kinase: synthesis, preliminary SAR, and biological activities.BDB Abbott Laboratories
16303309 31 Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.BDB Wyeth Research
10694412 15 Thermodynamics of substrate binding to the chaperone SecB.BDB Indian Institute of Science