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14 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27690435 20 Discovery and Development of Kelch-like ECH-Associated Protein 1. Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction Inhibitors: Achievements, Challenges, and Future Directions.EBI China Pharmaceutical University
27437072 6 Therapeutic Potential for Modulation of Nrf2-Keap-1 Signaling Pathway as Treatment for Diabetes and Other Disorders.EBI Therachem Research Medilab (India) Pvt. Ltd.
27031670 16 Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.EBI Astex Pharmaceuticals
26363505 9 Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators.EBI University of Illinois at Chicago
24512214 7 Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.EBI China Pharmaceutical University
23647822 3 Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.EBI Biogen Idec Inc.
23562243 11 Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction.EBI The State University of New Jersey
29534931 7 Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction.EBI University of East Anglia
30122040 23 Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors.EBI University of Illinois at Chicago
29750408 16 Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases.EBI University of Copenhagen
29407955 2 Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway.EBI China Pharmaceutical University
29117896 7 Discovery of a head-to-tail cyclic peptide as the Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency.EBI China Pharmaceutical University
29037947 8 Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor.EBI Keio University