The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28650658 |
54 |
Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization. |
Shandong University |
25893041 |
12 |
Discovery of a Dual PRMT5-PRMT7 Inhibitor. |
University of Toronto |
29870258 |
10 |
Protein Arginine Methyltransferase 5 (PRMT5) as an Anticancer Target and Its Inhibitor Discovery. |
Sun Yat-Sen University |
30034588 |
5 |
LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. |
Lilly Research Laboratories |
29628326 |
12 |
Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations. |
University of Jinan |
28135235 |
71 |
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED. |
Novartis Institutes for BioMedical Research |