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22 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26745812 8 Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.EBI Ludwig-Maximilians University
23583910 24 Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors.EBI Ludwig-Maximilians-Universit£t M£nchen
17760433 37 Influence of conformation on GRIND-based three-dimensional quantitative structure-activity relationship (3D-QSAR).EBI Universit£ di Torino
17981368 22 GRIND-based 3D-QSAR to predict inhibitory activity for similar enzymes, OSC and SHC.EBI CASMedChem Laboratory
1501233 7 2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase.EBI Istituto di Chimica Farmaceutica Applicata
22533316 10 Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells.EBI Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)
17027267 9 Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase.EBI Universit£ degli Studi del Piemonte Orientale A. Avogadro
12852766 22 Synthesis and structure-activity studies of novel orally active non-terpenoic 2,3-oxidosqualene cyclase inhibitors.EBI F. Hoffmann-La Roche Inc
22137785 6 Inhibitors of human 2,3-oxidosqualene cyclase (OSC) discovered by virtual screening.EBI Institute of Microbial Chemistry
20728352 5 Novel pyrrole- and 1,2,3-triazole-based 2,3-oxidosqualene cyclase inhibitors.EBI Institute of Microbial Chemistry
 4 Inhibition of oxidosqualene cyclase by substituted quinolizidinesEBI TBA
19119009 75 Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents.EBI Università di Torino
18467104 13 Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity.EBI Laboratoire GlaxoSmithKline
13678402 12 Oxidosqualene cyclase inhibitors as antimicrobial agents.EBI University of Utah
12747780 56 Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase.EBI Albert-Ludwigs-University of Freiburg
11150166 12 A novel series of 4-piperidinopyridine and 4-piperidinopyrimidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase.EBI AstraZeneca
9484504 14 29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase.EBI Università di Torino
9003518 23 Synthesis and inhibition studies of sulfur-substituted squalene oxide analogues as mechanism-based inhibitors of 2,3-oxidosqualene-lanosterol cyclase.EBI Simon Fraser University
24269162 84 NAD-based inhibitors with anticancer potential.EBI University of Minnesota
23937979 6 Discovery of N-(2,3,5-triazoyl)mycophenolic amide and mycophenolic epoxyketone as novel inhibitors of human IMPDH.EBI Hokkaido University
30322754 48 Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles.EBI The University of Queensland
29771525 4 NMR Biochemical Assay for Oxidosqualene Cyclase: Evaluation of Inhibitor Activities on Trypanosoma cruzi and Human Enzymes.EBI National Institute of Advanced Industrial Science and Technology (AIST)