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18 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26638045 58 Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors.EBI UiT The Arctic University of Norway
25559080 38 Additivity or cooperativity: which model can predict the influence of simultaneous incorporation of two or more functionalities in a ligand molecule?EBI The State University of New York
23988485 5 Synthesis and enzymatic evaluation of phosphoramidon and its▀ anomer: Anomerization ofa-l-rhamnose triacetate upon phosphitylation.EBI Jiangxi Science and Technology Normal University
22894131 4 Water mediated ligand functional group cooperativity: the contribution of a methyl group to binding affinity is enhanced by a COO(-) group through changes in the structure and thermodynamics of the hydration waters of ligand-thermolysin complexes.EBI The State University of New York
7783143 66 Hydroxamic acids as potent inhibitors of endothelin-converting enzyme from human bronchiolar smooth muscle.EBI Berlex Laboratories
8021926 41 New thiol inhibitors of neutral endopeptidase EC 3.4.24.11: synthesis and enzyme active-site recognition.EBI INSERM
8340909 14 Excursions in drug discovery.EBI Merck Research Laboratories
1588550 10 Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.EBI CIBA-GEIGY Corporation
12443790 3 Silanediol-based inhibitor of thermolysin.EBI State University of New York
 11 Thiol and hydroxamic acid containing inhibitors of endothelin converting enzymeEBI TBA
20494587 24 Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases.EBI University of Troms£
 2 Inhibitory stereochemistry of N-chloroacetyl-N-hydroxyleucine methyl ester for thermolysinEBI TBA
19072688 22 Discovery of potent thermolysin inhibitors using structure based virtual screening and binding assays.EBI University of Tromsø
12951085 10 Reversed hydroxamate-bearing thermolysin inhibitors mimic a high-energy intermediate along the enzyme-catalyzed proteolytic reaction pathway.EBI Pohang University of Science and Technology
9934463 6 Inhibition stereochemistry of hydroxamate inhibitors for thermolysin.EBI Pohang University of Science and Technology
9871678 8 Inhibition of thermolysin with nitrone-bearing substrate analogs: a new type of thermolysin inhibitors.EBI Pohang University of Science and Technology
9046341 44 Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.EBI CIBA-GEIGY Corporation
9046340 23 Ortho-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.EBI Novartis Pharmaceuticals Corporation