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19 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
24405703 72 4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: part 2. Pyridazine-based analogs.EBI Janssen Research and Development, LLC
24153205 21 4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: urea-based analogs.EBI Janssen Research and Development, LLC
23395660 48 Benzimidazole-carboxamides as potent and bioavailable stearoyl-CoA desaturase (SCD1) inhibitors from ligand-based virtual screening and chemical optimization.EBI Sanofi-Aventis Deutschland GmbH
23265904 54 Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1).EBI Merck Research Laboratories
21661758 39 Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.EBI Merck Frosst Centre for Therapeutic Research
22101133 26 Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series.EBI Merck Frosst Centre for Therapeutic Research
22047692 50 Nicotinic acids: liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy.EBI Merck Frosst Centre for Therapeutic Research
22209206 35 Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series.EBI Merck Frosst Centre for Therapeutic Research
21924609 28 Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors.EBI Merck Frosst Centre for Therapeutic Research
21871798 39 Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: from systemic to liver-targeting inhibitors.EBI Merck Frosst Centre for Therapeutic Research
21324691 24 N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors.EBI Pfizer Inc.
20933412 83 2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors.EBI Merck Frosst Centre for Therapeutic Research
20137926 43 SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors.EBI Merck Frosst Centre for Therapeutic Research
20004097 36 Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438).EBI Merck Frosst Centre for Therapeutic Research
19632834 16 Thiazole analog as stearoyl-CoA desaturase 1 inhibitor.EBI Merck Frosst Centre for Therapeutic Research
19577469 30 Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.EBI Gilead Sciences, Inc.
19394219 40 Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors.EBI CV Therapeutics, Inc