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255 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28244748 119 The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The"Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.EBI Virginia Commonwealth University
27933960 122 Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors.EBI National Institute on Drug Abuse
27080180 39 Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.EBI University of Arkansas for Medical Sciences
26935940 23 Emerging targets and new small molecule therapies in Parkinson's disease treatment.EBI School of Medicine of University of Electronic Science and Technology of China
26233799 15 Ethylenedioxy homologs of N-methyl-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrine.EBI Virginia Commonwealth University
25593099 57 Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template.EBI Wayne State University
25193229 102 Alpha-ethyltryptamines as dual dopamine-serotonin releasers.EBI Research Triangle Institute
24944732 37 Hybrid dopamine uptake blocker-serotonin releaser ligands: a new twist on transporter-focused therapeutics.EBI RTI International
1271416 10 Conformationally rigid amphetamine analogs as inhibitors of monoamine uptake by brain synaptosomes.EBI TBA
24900562 126 Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and antidepressant activity.EBI AstraZeneca
22082561 9 Characterisation of [¹¹C]PR04.MZ in Papio anubis baboon: a selective high-affinity radioligand for quantitative imaging of the dopamine transporter.EBI Johannes Gutenberg University
21486038 177 Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.EBI H. Lundbeck A/S
23022052 6 A novel spirocyclic tropanyl-¿²-isoxazoline derivative enhances citalopram and paroxetine binding to serotonin transporters as well as serotonin uptake.EBI Universit£ degli Studi di Milano
22749190 23 Wake-promoting agents: search for next generation modafinil: part IV.EBI Cephalon (France)
22546675 24 Wake promoting agents: search for next generation modafinil, lessons learned: part III.EBI Cephalon, Inc.
21344069 43 Structure-Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide) Analogues.EBI National Institute on Drug Abuse - Intramural Research Program
20036131 68 Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters.EBI University of Kentucky
19896846 44 Synthesis and monoamine transporter affinity of 3alpha-arylmethoxy-3beta-arylnortropanes.EBI University of New Orleans
18954038 62 Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic pain.EBI Neurocrine Biosciences, Inc.
18774292 72 Dual DAT/sigma1 receptor ligands based on 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-1-phenylpropan-1-ol.EBI National Institute on Drug Abuse-Intramural Research Program
19038547 62 1-Naphthyl and 4-indolyl arylalkylamines as selective monoamine reuptake inhibitors.EBI The State University of New York
18539031 126 Studies on the structure-activity relationship of bicifadine analogs as monoamine transporter inhibitors.EBI Neurocrine Biosciences, Inc.
18249549 54 Further structural optimization of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine and 1,4-diazabicyclo[3.3.1]nonane derivatives by introducing an exocyclic hydroxyl group: interaction with dopamine, serotonin, and norepinephrine transporters.EBI Wayne State University
18278854 20 Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity.EBI The University of Mississippi
17228858 236 Advances in development of dopaminergic aporphinoids.EBI Chinese Academy of Sciences
17399987 11 3-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-6-substituted-3,6-diazabicyclo[3.1.1]heptanes as novel potent dopamine uptake inhibitors.EBI Universit£ di Sassari
17489581 95 Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate.EBI School of Chemistry and Biochemistry
17407815 27 Tricyclic isoxazolines: identification of R226161 as a potential new antidepressant that combines potent serotonin reuptake inhibition and alpha2-adrenoceptor antagonism.EBI Johnson& Johnson Pharmaceutical Research& Development
17034144 72 Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.EBI National Institute on Drug Abuse-Intramural Research Program
16821765 29 Development of peptidic dopamine transporter inhibitors via aromatic modification-mediated conformational restriction.EBI Chinese Academy of Sciences
16213721 60 N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands.EBI National Institute on Drug Abuse--Intramural Research Program
16165350 11 The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines.EBI Wake Forest University Health Sciences
15857139 31 Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter.EBI Universit£ di Ferrara
15743177 43 Synthesis and biological evaluation of meperidine analogues at monoamine transporters.EBI University of New Orleans
15916437 90 Synthesis and monoamine transporter binding properties of 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters. Norepinephrine transporter selective compounds.EBI Research Triangle Institute
15537337 95 Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.EBI Acenta Discovery, Inc.
15456254 60 Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.EBI Wayne State University
15686927 39 Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency.EBI Yale University
15163183 92 Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring.EBI University of Illinois at Chicago
15027858 35 Synthesis and monoamine transporter binding of 2-(diarylmethoxymethyl)-3 beta-aryltropane derivatives.EBI University of New Orleans
14711303 115 Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.EBI Research Triangle Institute
15189035 67 Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.EBI National Institute on Drug Abuse--Intramural Research Program
12672245 54 Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors.EBI School of Chemistry and Biochemistry
12646032 30 High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.EBI Wayne State University
14640559 405 Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.EBI FAES FARMA S A
12825932 61 Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter.EBI National Institute on Drug Abuse
12801223 71 Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.EBI NIDA-IRP
12747792 12 Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.EBI Wayne State University
12723962 69 Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.EBI Georgetown University Medical Center
12723940 145 2002 Medicinal Chemistry Division Award address: monoamine transporters and opioid receptors. Targets for addiction therapy.EBI Research Triangle Institute
11960503 140 Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.EBI Georgetown University Medical Center
11881989 7 Synthesis and biological evaluation of 2-substituted 3beta-tolyltropane derivatives at dopamine, serotonin, and norepinephrine transporters.EBI University of New Orleans
11806716 44 Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules.EBI Wayne State University
12213053 117 Mazindol analogues as potential inhibitors of the cocaine binding site at the dopamine transporter.EBI Drew University
12190324 15 Synthesis and transporter binding properties of 3beta-[4'-(phenylalkyl, -phenylalkenyl, and -phenylalkynyl)phenyl]tropane-2beta-carboxylic acid methyl esters: evidence of a remote phenyl binding domain on the dopamine transporter.EBI Research Triangle Institute
12109901 45 SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement.EBI Georgetown University Medical Center
11300876 47 Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.EBI Wayne State University
11170654 72 Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes.EBI National Institute on Drug Abuse-Intramural Research Program
11728190 10 Novel tropane-based irreversible ligands for the dopamine transporter.EBI National Institute on Drug Abuse-Intramural Research Program
11689080 43 Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.EBI National Institute of Diabetes and Digestive and Kidney Diseases
11334571 79 Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors.EBI Georgetown University Medical Center
10737754 30 Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors.EBI Georgetown University Medical Center
10737741 50 Highly selective chiral N-substituted 3alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues for the dopamine transporter: synthesis and comparative molecular field analysis.EBI National Institute on Drug Abuse-Intramural Research Program
11123996 21 Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.EBI National Institute of Diabetes and Digestive and Kidney Diseases
11123994 72 Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909).EBI National Institute of Diabetes and Digestive and Kidney Diseases
10966747 7 Chemical synthesis and pharmacology of 6- and 7-hydroxylated 2-carbomethoxy-3-(p-tolyl)tropanes: antagonism of cocaine's locomotor stimulant effects.EBI Georgetown University Medical Center
10821718 69 Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.EBI Georgetown University Medical Center
10072685 82 Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-(aminomethyl)-3-phenylbicyclo[2.2.2]- and -[2.2.1]alkane dopamine uptake inhibitors.EBI School of Chemistry and Biochemistry
10579846 68 Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.EBI School of Chemistry and Biochemistry
10543888 60 Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.EBI National Institute on Drug Abuse-Intramural Research Program
10479283 74 CoMFA study of novel phenyl ring-substituted 3alpha-(diphenylmethoxy)tropane analogues at the dopamine transporter.EBI National Institute on Drug Abuse - Intramural Research Program
9526561 22 (-)-3 beta-Substituted ecgonine methyl esters as inhibitors for cocaine binding and dopamine uptake.EBI University of Maryland
9836615 106 Synthesis and biological properties of new 2beta-alkyl- and 2beta-aryl-3-(substituted phenyl)tropane derivatives: stereochemical effect of C-3 on affinity and selectivity for neuronal dopamine and serotonin transporters.EBI Georgetown University Medical Center
9804688 51 Modified ibogaine fragments: synthesis and preliminary pharmacological characterization of 3-ethyl-5-phenyl-1,2,3,4,5, 6-hexahydroazepino[4,5-b]benzothiophenes.EBI University of Minnesota
9457247 39 Synthesis and ligand binding of tropane ring analogues of paroxetine.EBI Research Triangle Institute
9632375 8 Synthesis and dopamine transporter affinity of the four stereoisomers of (+/-)-2-(methoxycarbonyl)-7-methyl-3-phenyl-7-azabicyclo[2.2.1]heptane.EBI University of New Orleans
9632371 28 2beta-Substituted analogues of 4'-iodococaine: synthesis and dopamine transporter binding potencies.EBI University of Oklahoma Health Sciences Center
9599245 23 Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.EBI Georgetown University Medical Center
9135033 36 Synthesis and ligand binding of nortropane derivatives: N-substituted 2beta-carbomethoxy-3beta-(4'-iodophenyl)nortropane and N-(3-iodoprop-(2E)-enyl)-2beta-carbomethoxy-3beta-(3',4'-disubstituted phenyl)nortropane. New high-affinity and selective compounds for the dopamine transporter.EBI INSERM
9111298 18 Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3beta-phenyltropane-2beta-carboxylic acid esters.EBI Research Triangle Institute
9083474 12 Synthesis, dopamine transporter affinity, dopamine uptake inhibition, and locomotor stimulant activity of 2-substituted 3 beta-phenyltropane derivatives.EBI University of New Orleans
9083473 33 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.EBI National Institutes of Health
9435910 23 Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.EBI University of New Orleans
9435903 14 Isothiocyanate derivatives of 9-[3-(cis-3,5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole): irreversible ligands for the dopamine transporter.EBI National Institute on Drug Abuse-Intramural Research Program
9397165 27 3 Beta-(4-ethyl-3-iodophenyl)nortropane-2 beta-carboxylic acid methyl ester as a high-affinity selective ligand for the serotonin transporter.EBI Research Triangle Institute
9258354 10 Synthesis and ligand binding studies of 4'-iodobenzoyl esters of tropanes and piperidines at the dopamine transporter.EBI University of Oklahoma
8691489 12 Synthesis and ligand binding of eta(6)-(2beta-carbomethoxy-3beta-phenyltropane) transition metal complexes.EBI University of New Orleans
8632426 62 Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs.EBI School of Chemistry and Biochemistry
8941387 10 Synthesis and dopamine transporter affinity of 2-(methoxycarbonyl)-9-methyl-3-phenyl-9-azabicyclo[3.3.1]nonane derivatives.EBI University of New Orleans
8941383 146 Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909).EBI National Institute of Diabetes and Digestive and Kidney Diseases
8863789 31 3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.EBI Research Triangle Institute
8831768 65 Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.EBI Research Triangle Institute
8558525 60 N-substituted analogs of 2 beta-carbomethoxy-3 beta- (4'-iodophenyl)tropane (beta-CIT) with selective affinity to dopamine or serotonin transporters in rat forebrain.EBI Research Biochemicals International
8709106 89 Synthesis, ligand binding, and quantitative structure-activity relationship study of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes: evidence for an electrostatic interaction at the 2 beta-position.EBI Research Triangle Institute
7562926 81 Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors.EBI National Institutes of Health
7830281 237 Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.EBI Research Triangle Institute
7658431 18 Synthesis and ligand binding study of 3 beta-(4'-substituted phenyl)-2 beta-(heterocyclic)tropanes.EBI Research Triangle Institute
7636872 24 Chemistry and biology of the 2 beta-alkyl-3 beta-phenyl analogues of cocaine: subnanomolar affinity ligands that suggest a new pharmacophore model at the C-2 position.EBI Mayo Foundation for Medical Education and Research
8176704 40 Synthesis of 2 beta-acyl-3 beta-aryl-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites in rat striatum and frontal cortex.EBI Wake Forest University
8164265 42 Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.EBI National Institute on Drug Abuse
7966147 14 Synthesis, cocaine receptor affinity, and dopamine uptake inhibition of several new 2 beta-substituted 3 beta-phenyltropanes.EBI University of New Orleans
7932572 7 Structure-activity relationship studies of N-sulfonyl analogs of cocaine: role of ionic interaction in cocaine binding.EBI Trophix Pharmaceuticals, Inc.
8071935 25 Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.EBI Research Triangle Institute
8057273 9 Novel 3 alpha-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioral profiles.EBI National Institutes of Health
8035432 5 Synthesis of substituted 3-carbamoylecgonine methyl ester analogues: irreversible and photoaffinity ligands for the cocaine receptor/dopamine transporter.EBI University of Maryland
8201589 11 N-omega-fluoroalkyl analogs of (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters.EBI Research Biochemicals International
8182712 14 Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents.EBI University of Tennessee Medical Center at Knoxville 37920.
8098066 39 Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites.EBI National Institute of Diabetes and Digestive and Kidney Diseases
8258830 87 Further studies of the structure-activity relationships of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine. Synthesis and evaluation of 1-(2-benzo[b]thienyl)-N,N-dialkylcyclohexylamines at dopamine uptake and phencyclidine binding sites.EBI National Institute of Diabetes and Digestive and Kidney Diseases
8246225 20 Analysis of cocaine receptor site ligand binding by three-dimensional Voronoi site modeling approach.EBI University of Michigan
8411004 48 3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogues of cocaine: affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters.EBI Research Triangle Institute
1552510 178 Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter.EBI Research Triangle Institute
1469704 5 Structure-activity relationship studies of cocaine: replacement of the C-2 ester group by vinyl argues against H-bonding and provides an esterase-resistant, high-affinity cocaine analogue.EBI Mayo Foundation for Education and Research
1619622 51 Isopropyl and phenyl esters of 3 beta-(4-substituted phenyl)tropan-2 beta-carboxylic acids. Potent and selective compounds for the dopamine transporter.EBI Research Triangle Institute
1588560 19 Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.EBI Research Triangle Institute
1732521 12 N-modified analogues of cocaine: synthesis and inhibition of binding to the cocaine receptor.EBI Research Triangle Institute
1732520 21 2 beta-substituted analogues of cocaine. Synthesis and inhibition of binding to the cocaine receptor.EBI Research Triangle Institute
1895292 16 Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters.EBI Research Triangle Institute
2033595 5 Synthesis and receptor binding of N-substituted tropane derivatives. High-affinity ligands for the cocaine receptor.EBI Research Biochemicals Inc.
2002468 8 Synthesis and ligand binding of cocaine isomers at the cocaine receptor.EBI Research Triangle Institute
1920365 8 [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: high-affinity SPECT radiotracer of monoamine reuptake sites in brain.EBI Research Biochemicals Inc.
2903929 143 Antihypertensive activity in a series of 1-piperazino-3-phenylindans with potent 5-HT2-antagonistic activity.EBI H. Lundbeck A/S
3039136 328 Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.EBI TBA
2999402 207 3-Phenyl-1-indanamines. Potential antidepressant activity and potent inhibition of dopamine, norepinephrine, and serotonin uptake.EBI TBA
6747993 69 Pyrroloisoquinoline antidepressants. Potent, enantioselective inhibition of tetrabenazine-induced ptosis and neuronal uptake of norepinephrine, dopamine, and serotonin.EBI TBA
6492080 195 Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.EBI TBA
6134833 91 Neuroleptic activity and dopamine-uptake inhibition in 1-piperazino-3-phenylindans.EBI TBA
7452682 76 3-(4-Piperidinylalkyl)indoles, selective inhibitors of neuronal 5-hydroxytryptamine uptake.EBI TBA
15115403 48 Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters.EBI National Institute of Diabetes and Digestive and Kidney Diseases
15149693 56 The effect of 6-substituted-4',4"-difluorobenztropines on monoamine transporters and the muscarinic M1 receptor.EBI National Institute on Drug Abuse--Intramural Research Program
12699762 27 Design, synthesis, and activity of novel cis- and trans-3,6-disubstituted pyran biomimetics of 3,6-disubstituted piperidine as potential ligands for the dopamine transporter.EBI Wayne State University
12565962 41 Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors.EBI University of Michigan
14505672 78 Synthesis and pharmacological evaluation of (Z)-9-(heteroarylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes: thiophene analogues as potent norepinephrine transporter inhibitors.EBI Georgetown University Medical Center
11909701 35 Thiophene derivatives: a new series of potent norepinephrine and serotonin reuptake inhibitors.EBI Georgetown University Medical Center
12161139 11 Synthesis and dopamine transporter binding affinities of 3alpha-benzyl-8-(diarylmethoxyethyl)-8-azabicyclo[3.2.1]octanes.EBI University of New Orleans
12127543 26 Identification of a novel partial inhibitor of dopamine transporter among 4-substituted 2-phenylquinazolines.EBI Southern Research Institute
12067559 34 Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.EBI University of Michigan
11354356 42 Pharmacophore-based discovery of 3,4-disubstituted pyrrolidines as a novel class of monoamine transporter inhibitors.EBI Georgetown University Medical Center
11277529 14 Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter.EBI Universit£ di Ferrara
11720867 24 [3-cis-3,5-Dimethyl-(1-piperazinyl)alkyl]-bis-(4'-fluorophenyl)amine analogues as novel probes for the dopamine transporter.EBI National Institute on Drug Abuse - Intramural Research Program
11714614 11 Synthesis and binding affinities of 2 beta-(3-iodoallyloxycarbonyl)-3 beta-(4-substituted-aryl)tropane analogues as ligands for the dopamine transporter studies.EBI Inha University
11527726 15 Rational design and synthesis of novel 2,5-disubstituted cis- and trans-piperidine derivatives exhibiting differential activity for the dopamine transporter.EBI Wayne State University
11514143 71 Sar studies of piperidine-based analogues of cocaine. Part 3: oxadiazoles.EBI Georgetown University Medical Center
11078197 65 3alpha-(4-Substituted phenyl)nortropane-2beta-carboxylic acid methyl esters show selective binding at the norepinephrine transporter.EBI Research Triangle Institute
10937724 56 Synthesis and biological evaluation of 1-azabicyclo-[3.2.1]octanes: new dopamine transporter inhibitors.EBI Georgetown University Medical Center
10888328 17 An enantioselective synthesis and biobehavioral evaluation of 7-fluoro-3-(p-fluorophenyl)-2-propyltropanes.EBI Georgetown University Medical Center
10612593 33 N-phenylalkyl-substituted tropane analogs of boat conformation with high selectivity for the dopamine versus serotonin transporter.EBI Georgetown University Medical Center
10406650 18 Synthesis of 8-Oxa analogues of norcocaine endowed with interesting cocaine-like activity.EBI Georgetown University Medical Center
9871604 114 Synthesis of a potent wide-spectrum serotonin-, norepinephrine-, dopamine-reuptake inhibitor (SNDRI) and a species-selective dopamine-reuptake inhibitor based on the gamma-amino alcohol functional group.EBI Hong Kong University of Science and Technology
9934496 27 Synthesis and transporter binding properties of (R)-2 beta, 3 beta- and (R)-2 alpha, 3 alpha-diaryltropanes.EBI Research Triangle Institute
 10 Further evidence for a dopamine reuptake pharmacophore. The effect of N-methylation on Threo-methylphenidate and its analogsEBI TBA
 28 Synthesis and evaluation of novel-N-[2-(bis-aryl-methoxy)ethyl-N-aralkyl-,-alkanediamines as potent and selective dopamine reuptake inhibitors: Seco analogs of GBR12935 and GBR12909EBI TBA
 8 Differential binding and dopamine uptake activity of cocaine analogues modified at nitrogenEBI TBA
22341942 18 Wake-promoting agents: search for next generation modafinil: part II.EBI Cephalon, Inc.
22264475 10 Wake-promoting agents: search for next generation modafinil: part I.EBI Cephalon, Inc.
22055716 45 Further structure-activity relationship studies on 8-substituted-3-[2-(diarylmethoxyethylidenyl)]-8-azabicyclo[3.2.1]octane derivatives at monoamine transporters.EBI University of New Orleans
21446715 43 Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.EBI Wayne State University
21093273 154 Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.EBI Sepracor Inc.
20980153 83 Synthesis and structure-activity studies of benzyl ester meperidine and normeperidine derivatives as selective serotonin transporter ligands.EBI University of New Orleans
20971650 26 Discovery and synthesis of novel luteolin derivatives as DAT agonists.EBI Zhengzhou University
20846865 80 Quantitative structure-activity relationship studies of threo-methylphenidate analogs.EBI Institute of Technology
20672825 67 Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) analogues at monoamine transporters.EBI National Institute on Drug Abuse-Intramural Research Program
20022503 15 Synthesis and antidepressant activity of optical isomers of 2-(4-benzylpiperazin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl) propan-1-ol (SIPI5056).EBI Institute of Pharmaceutical Industry
19640707 12 Design and synthesis of (2R,3S)-iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter.EBI University of Glasgow
19577467 2 Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter.EBI Institutet
8676127 40 Effects of Various Isoquinoline Alkaloids on In Vitro 3H-Dopamine Uptake by Rat Striatal SynaptosomesEBI TBA
 18 N-Phthalimidoalkyl derivatives of 2β-carbomethoxy-3β-(4′-iodophenyl)tropane (β-CIT): Brain monoamine transporter affinityEBI TBA
 4 A novel photoaffinity label for the dopamine transporter based on N-substituted 3α-[bis(4′-fluorophenyl)methoxy]tropaneEBI TBA
18762424 4 New iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter.EBI University of Glasgow
17658253 23 New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET.EBI Institut für Interdisziplinäre Isotopenforschung
17350257 54 Synthesis of enantiomerically pure milnacipran analogs and inhibition of dopamine, serotonin, and norepinephrine transporters.EBI University of Oslo
17328523 36 Novel sigma receptor ligands: synthesis and biological profile.EBI University of Catania
17127069 96 DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods.EBI University Heights
17095215 25 Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER.EBI Institute for Degenerative Diseases
17064081 10 Design and synthesis of a novel photoaffinity ligand for the dopamine and serotonin transporters based on 2beta-carbomethoxy-3beta-biphenyltropane.EBI National Institute on Drug Abuse-Intramural Research Program
16908151 24 Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(4'-p-substituted phenyl)-piperidine analogs of cocaine.EBI Yale University
16905316 42 Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters.EBI University of Kentucky
16821783 60 Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and noEBI Wayne State University
16335921 99 Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors.EBI University of Illinois at Chicago
16236497 48 Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[aryl or heteroaryl]phenyltropanes.EBI Yale University
16033275 7 Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.EBI Wayne State University
15863297 57 Discovery of novel conformationally constrained tropane-based biaryl and arylacetylene ligands as potent and selective norepinephrine transporter inhibitors and potential antidepressants.EBI Acenta Discovery, Inc.
15771448 187 Discovery of a new series of centrally active tricyclic isoxazoles combining serotonin (5-HT) reuptake inhibition with alpha2-adrenoceptor blocking activity.EBI Johnson & Johnson Pharmaceutical Research & Development
15566284 12 Novel azido and isothiocyanato analogues of [3-(4-phenylalkylpiperazin-1-yl)propyl]bis(4-fluorophenyl)amines as potential irreversible ligands for the dopamine transporter.EBI National Institute on Drug Abuse
15482938 45 Synthesis and amine transporter affinities of novel phenyltropane derivatives as potential positron emission tomography (PET) imaging agents.EBI Harvard Medical School
15080991 38 Synthesis and monoamine transporter affinity of 3'-analogs of 2-beta-carbomethoxy-3-beta-(4'-iodophenyl)tropane (beta-CIT).EBI Yale School of Medicine
15026075 51 Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites.EBI State University of New York
12672255 18 Synthesis and evaluation of dopamine and serotonin transporter inhibition by oxacyclic and carbacyclic analogues of methylphenidate.EBI Organix Inc.
12672246 68 Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.EBI NIDDK
12657288 102 Further exploration of 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]piperazine (GBR 12909): role of N-aromatic, N-heteroaromatic, and 3-oxygenated N-phenylpropyl substituents on affinity for the dopamine and serotonin transporter.EBI NIDDK
12639545 37 Synthesis of dopamine transporter selective 3-[2-(diarylmethoxyethylidene)]-8-alkylaryl-8-azabicyclo[3.2.1]octanes.EBI University of New Orleans
12565970 44 Synthesis and dopamine transporter affinity of chiral 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-hydroxypropyl)piperazines as potential cocaine abuse therapeutic agents.EBI National Institute of Diabetes and Digestive and Kidney Diseases
12361398 19 New PET imaging agent for the serotonin transporter: [(18)F]ACF (2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine).EBI University of Pennsylvania
12213055 71 Three-dimensional quantitative structure-activity relationships of mazindol analogues at the dopamine transporter.EBI National Institute on Drug Abuse-Intramural Research Program/NIH
12213054 38 Benzo- and cyclohexanomazindol analogues as potential inhibitors of the cocaine binding site at the dopamine transporter.EBI Drew University
11965364 36 Enantioselective synthesis of S-(+)-2beta-carboalkoxy-3alpha-[bis(4-fluorophenyl)methoxy]tropanes as novel probes for the dopamine transporter.EBI National Institute on Drug Abuse-Intramural Research Program
11958976 30 Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters.EBI State University of New York
11882001 34 Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine.EBI National Institute of Diabetes and Digestive and Kidney Diseases
11881994 42 Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.EBI INSERM
11714608 30 Synthesis and biological evaluation of a series of novel N- or O-fluoroalkyl derivatives of tropane: potential positron emission tomography (PET) imaging agents for the dopamine transporter.EBI Alcohol and Drug Abuse Research Center
11356113 18 Enantioselective syntheses of dopaminergic (R)- and (S)-benzyltetrahydroisoquinolines.EBI Universidad de Valencia
11334561 63 Synthesis of 2beta-acyl-3beta-(substituted naphthyl)-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites.EBI State University of New York
11229754 28 Synthesis and monoamine transporter affinity of 3beta-(4-(2-pyrrolyl)phenyl)-8-azabicycl.EBI State University of New York
11133081 33 A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents.EBI Georgetown University Medical Center
10969967 34 Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(2''-, 3''- or 4''-substituted) biphenyltropanes.EBI Yale University
10937721 9 Inhibition of dopamine receptors by endogenous amines: binding to striatal receptors and pharmacological effects on locomotor activity.EBI University of Tokyo
10669562 29 Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies.EBI Georgetown University Medical Center
10612583 27 Synthesis, dopamine and serotonin transporter binding affinities of novel analogues of meperidine.EBI University of New Orleans
10585212 138 Oxygenated analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents.EBI National Institute of Diabetes and Digestive and Kidney Diseases
9871666 4 Design and synthesis of a biotinylated dopamine transporter ligand for the purification and labeling of dopaminergic neurons.EBI Novartis Pharma Inc.
9703474 21 Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.EBI Organix Inc.
9513598 20 Potent and selective ligands for the dopamine transporter (DAT): structure-activity relationship studies of novel 4-[2-(diphenylmethoxy)ethyl]-1-(3-phenylpropyl)piperidine analogues.EBI Organix Inc.
9484494 2 Specificity of diastereomers of [99mTc]TRODAT-1 as dopamine transporter imaging agents.EBI University of Pennsylvania
9435902 60 Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter.EBI National Institute on Drug Abuse
9406593 5 1-[1-2-Benzo[b]thiopheneyl)cyclohexyl]piperidine hydrochloride (BTCP) yields two active primary metabolites in vitro: synthesis, identification from rat liver microsome extracts, and affinity for the neuronal dopamine transporter.EBI INSERM
9397171 81 N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters.EBI University of Minnesota
9057857 169 Heteroaromatic analogs of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as high-affinity dopamine reuptake inhibitors.EBI National Institute of Diabetes and Digestive and Kidney Diseases
9016326 38 Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.EBI Organix Inc.
8960553 60 Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.EBI Drew University
8691453 42 Synthesis of 3 beta-aryl-8-azabicyclo[3.2.1]octanes with high binding affinities and selectivities for the serotonin transporter site.EBI State University of New York
8576918 38 Structure-activity relationship studies of novel 4-[2-[bis(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs: synthesis and biological evaluation at the dopamine and serotonin transporter sites.EBI Organix Inc.
8515426 12 Inhibition and inactivation of presynaptic cholinergic markers using redox-reactive choline analogs.EBI University of Toledo
7562944 16 In vivo and in vitro studies on the neurotoxic potential of 6-hydroxydopamine analogs.EBI University of Oklahoma
3735309 50 Selective monoamine oxidase inhibitors. 3. Cyclic compounds related to 4-aminophenethylamine. Preparation and neuron-selective action of some 5-(2-aminoethyl)-2,3-dihydroindoles.EBI TBA
1613745 1 Synthesis of carbon-11 labeled iodinated cocaine derivatives and their distribution in baboon brain measured using positron emission tomography.EBI Brookhaven National Laboratory
16339913 6 Pharmacological characterization of (E)-N-(4-fluorobut-2-enyl)-2beta-carbomethoxy-3beta-(4'-tolyl)nortropane (LBT-999) as a highly promising fluorinated ligand for the dopamine transporter.BDB Univ. Tours
15879005 27 Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue.BDB Duquesne University
12761331 97 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro.BDB Case Western Reserve University
12721338 61 N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties.BDB Pudue Pharma Discovery Research
12649362 8 Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidine-3alpha-carboxylate, a piperidine-based analog of cocaine.BDB Georgetown University
12023542 23 Effects of norepinephrine and serotonin transporter inhibitors on hyperactivity induced by neonatal 6-hydroxydopamine lesioning in rats.BDB Harvard University
11961053 26 Biochemical and behavioral characterization of novel methylphenidate analogs.BDB Mercer University
11454918 90 S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine.BDB Institut de Recherches Servier
11438309 51 The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound.BDB Janssen Research Foundation
11082453 77 ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse.BDB Abbott Laboratories
11071707 71 Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin.BDB NIH
10773045 45 Characterization of a tropane radioligand, [(3)H]2beta-propanoyl-3beta-(4-tolyl) tropane ([(3)H]PTT), for dopamine transport sites in rat brain.BDB Wake Forest University
10611634 78 Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states.BDB Institut de Recherches Servier, Centre de Recherches de Croissy
10379421 134 Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding.BDB TBA
10336510 53 Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.BDB Virginia Commonwealth University
9223589 17 N-(3-lodoprop-2E-enyl)-2beta-carbomethoxy-3beta-(3',4'-dichloro phenyl)nortropane (beta-CDIT), a tropane derivative: pharmacological characterization as a specific ligand for the dopamine transporter in the rodent brain.BDB INSERM U316
8996185 121 Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity.BDB Synthélabo Recherche
8935801 586 Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.BDB Janssen Research Foundation
8424846 7 LY248686, a new inhibitor of serotonin and norepinephrine uptake.BDB Eli Lilly and Company
6310078 55 Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin.BDB Pfizer Inc.,
6123593 24 A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain.BDB Eli Lilly and Company
3790168 23 Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative.BDB Wyeth Laboratories, Inc.
3419539 56 Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers.BDB Organon International
2905001 64 McN-5652: a highly potent inhibitor of serotonin uptake.BDB McNeil Pharmaceutical
2580950 69 Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of dopamine, noradrenaline, and serotonin.BDB Lundbeck AIS
2531826 24 [125]I-spectramide: a novel benzamide displaying potent and selective effects at the D2 dopamine receptor.BDB NIDA Addiction Research Center
2530094 94 The dopamine inhibitor GBR 12909: selectivity and molecular mechanism of action.BDB Novo Industri A/S
17602602 117 Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.BDB Research Triangle Institute
18393401 70 Design and Synthesis of 2- and 3-Substituted-3-phenylpropyl Analogs of 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: Role of Amino, Fluoro, Hydroxyl, Methoxyl, Methyl, Methylene, and Oxo Substituents on Affinity fBDB National Taiwan University