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154 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
12372505 120 Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands.EBI Abbott Laboratories
12113835 176 Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 1.EBI Abbott Laboratories
10560733 19 4-Chlorobenzyl sulfonamide and sulfamide derivatives of histamine homologues: the design of potent histamine H3 receptor antagonists.EBI The James Black Foundation
10406649 31 From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists.EBI The James Black Foundation
25827402 54 3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activity.EBI Teva Global R&D.
25218907 18 Studies on molecular properties prediction and histamine H3 receptor affinities of novel ligands with uracil-based motifs.EBI University of Catania
24745967 19 Benzylpiperidine variations on histamine H3 receptor ligands for improved drug-likeness.EBI Johann Wolfgang Goethe University
24513042 22 Discovery of (1R,6S)-5-[4-(1-cyclobutyl-piperidin-4-yloxy)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one (R,S-4a): histamine H(3) receptor inverse agonist demonstrating potent cognitive enhancing and wake promoting activity.EBI Teva Pharmaceutical Global R&D
24269482 35 Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists.EBI GlaxoSmithKline R&D
24161834 17 The discovery of the benzazepine class of histamine H3 receptor antagonists.EBI GlaxoSmithKline R&D
24139584 17 Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)phenyl] amide as histamine H(3) receptor antagonist for the treatment of depression.EBI Sanofi US
24050887 49 Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists.EBI Merck Research Laboratories
24035485 48 Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity.EBI Merck Research Laboratories
23769643 28 Synthesis, characterization, and biological assessment of the four stereoisomers of the H(3) receptor antagonist 5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl)phenyl]benzamide.EBI Sanofi US
23591112 4 Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part II).EBI Sanofi US
23591110 28 Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part I).EBI Sanofi US
24900691 4 Novel thiazolobenzodiazepines as inhibitors of histamine h3 receptor.EBI Dart Neuroscience LLC
23535326 10 Novel and highly potent histamine H3 receptor ligands. Part 3: an alcohol function to improve the pharmacokinetic profile.EBI Bioprojet-Biotech
22222138 40 Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chain.EBI Universit£ degli Studi di Parma
20171098 20 Rigidified 2-aminopyrimidines as histamine H4 receptor antagonists: effects of substitution about the rigidifying ring.EBI Abbott Laboratories
19524331 33 Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.EBI Johnson& Johnson Pharmaceutical Research& Development
18990469 23 Non-imidazole histamine H3 ligands, part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives.EBI Medical University
18976927 83 Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity.EBI Universit£ degli Studi di Parma
14640554 31 N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists.EBI Freie Universit£t Berlin
10794692 15 Characterization of the binding site of the histamine H(3) receptor. 2. Synthesis, in vitro pharmacology, and QSAR of a series of monosubstituted benzyl analogues of thioperamide.EBI Vrije Universiteit
10737740 57 Histaprodifens: synthesis, pharmacological in vitro evaluation, and molecular modeling of a new class of highly active and selective histamine H(1)-receptor agonists.EBI Freie Universit£t Berlin
9258364 10 H3-receptor antagonists: synthesis and structure-activity relationships of para- and meta-substituted 4(5)-phenyl-2-[[2-[4(5)-imidazolyl]ethyl]thio]imidazoles.EBI Universit£ degli Studi di Parma
7830269 9 Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole.EBI Vrije Universiteit Amsterdam
7783156 35 New analogs of burimamide as potent and selective histamine H3 receptor antagonists: the effect of chain length variation of the alkyl spacer and modifications of the N-thiourea substituent.EBI Vrije Universiteit Amsterdam
12657274 109 Synthesis and SAR of aminoalkoxy-biaryl-4-carboxamides: novel and selective histamine H3 receptor antagonists.EBI Abbott Laboratories
12113836 162 Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 2: binding preference for D-amino acids motifs.EBI Abbott Laboratories
9873585 30 N alpha-alkylated derivatives of 2-phenylhistamines: synthesis and in vitro activity of potent histamine H1-receptor agonists.EBI Freie Universit£t Berlin
 10 Diphenylmethyl ethers: synthesis and histamine H3-receptor antagonist in vitro and in vivo activityEBI TBA
22483590 5 Radiofluorinated histamine H3 receptor antagonist as a potential probe for in vivo PET imaging: radiosynthesis and pharmacological evaluation.EBI ETH Zurich (Swiss Federal Institute of Technology)
21928839 51 Discovery of two clinical histamine H(3) receptor antagonists: trans-N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764).EBI Pfizer Inc.
21062081 47 Histamine H3 receptor as a drug discovery target.EBI TBA
24900450 44 Discovery of a potent thiadiazole class of histamine h3 receptor antagonist for the treatment of diabetes.EBI TBA
22578490 35 Synthesis and evaluation of 4- and 5-pyridazin-3-one phenoxypropylamine analogues as histamine-3 receptor antagonists.EBI Cephalon, Inc.
22450133 64 Substituted phenoxypropyl-(R)-2-methylpyrrolidine aminomethyl ketones as histamine-3 receptor inverse agonists.EBI Cephalon, Inc.
22617490 23 Synthesis of constrained benzocinnolinone analogues of CEP-26401 (irdabisant) as potent, selective histamine H3 receptor inverse agonists.EBI Cephalon, Inc.
22464130 27 Fused bicycles as arylketone bioisosteres leading to potent, orally active thiadiazole H3 antagonists.EBI Merck Research Laboratories
22313242 146 2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one derivatives as potent and selective histamine-3 receptor antagonists.EBI Pfizer Inc.
22313227 78 Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.EBI National Institute of Mental Health
22365751 45 Synthesis and evaluation of a new series of 1'-cyclobutyl-6-(4-piperidyloxy)spiro[benzopyran-2,4'-piperidine] derivatives as high affinity and selective histamine-3 receptor (H3R) antagonists.EBI Cephalon, Inc.
21906941 94 Synthesis and structure-activity relationships of 4,5-fused pyridazinones as histamine H3 receptor antagonists.EBI Cephalon, Inc.
21782432 62 Identification of pyridazin-3-one derivatives as potent, selective histamine H3 receptor inverse agonists with robust wake activity.EBI Cephalon, Inc.
21824776 31 Amine-constrained pyridazinone histamine H3 receptor antagonists.EBI Cephalon Inc.
21634396 55 Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist.EBI Cephalon, Inc.
20875743 90 Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relaEBI Pfizer Inc.
20561786 77 Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development.EBI Johnson& Johnson Pharmaceutical Research& Development L.L.C.
19456097 89 5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity.EBI F. Hoffmann-La Roche Ltd.
19329325 20 Diether derivatives of homo- or substituted piperidines as non-imidazole histamine H3 receptor ligands.EBI Jagiellonian University Medical College
18194865 25 A new family of H3 receptor antagonists based on the natural product Conessine.EBI Arena Pharmaceuticals
18077160 126 In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.EBI Abbott Laboratories
18052318 30 4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonists.EBI GlaxoSmithKline Medicines REsearch Centre
15634000 57 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention.EBI Abbott Laboratories
12672253 60 Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.EBI Freie Universit£t Berlin
12190321 55 Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties.EBI Freie Universit£t Berlin
11356102 16 Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.EBI De Novo Pharmaceuticals
11052804 41 Novel histamine H(3)-receptor antagonists with carbonyl-substituted 4-(3-(phenoxy)propyl)-1H-imidazole structures like ciproxifan and related compounds.EBI Freie Universit£t Berlin
 4 Diastereoselective synthesis of trans-2-(1-triphenylmethyl-1H-imidazol-4-yl)cyclopropanecarboxylic acids: key intermediates for the preparation of potent and chiral histamine H3 receptor agentsEBI TBA
22297111 32 Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity.EBI Cephalon, Inc.
22290075 60 4-phenoxypiperidine pyridazin-3-one histamine H(3) receptor inverse agonists demonstrating potent and robust wake promoting activity.EBI Cephalon, Inc.
22197136 29 Synthesis and structure-activity relationship of 5-pyridazin-3-one phenoxypiperidines as potent, selective histamine H(3) receptor inverse agonists.EBI Cephalon, Inc.
22172695 28 Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: discovery of (R)-1-(2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916).EBI Arena Pharmaceuticals
22153663 59 Ligand based design of novel histamine H4 receptor antagonists; fragment optimization and analysis of binding kinetics.EBI Griffin Discoveries BV
22153342 60 Synthesis and evaluation of 4-alkoxy-[1'-cyclobutyl-spiro(3,4-dihydrobenzopyran-2,4'-piperidine)] analogues as histamine-3 receptor antagonists.EBI Cephalon, Inc.
22142542 73 4,5-dihydropyridazin-3-one derivatives as histamine H3 receptor inverse agonists.EBI Cephalon, Inc.
22014551 33 Synthesis and evaluation of pyridone-phenoxypropyl-R-2-methylpyrrolidine analogues as histamine H3 receptor antagonists.EBI Cephalon, Inc.
21944855 30 Synthesis and evaluation of pyridazinone-phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activity.EBI Cephalon, Inc.
21937153 46 Recent progress in synthesis and bioactivity studies of indolizines.EBI University of Botswana
21783360 52 Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series.EBI Bioprojet-Biotech
19577344 43 Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.EBI Johnson& Johnson Pharmaceutical Research and Development
21498080 45 N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands.EBI Jagiellonian University Medical College
20945906 33 Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain.EBI Abbott Laboratories
20833043 28 Investigation of 4-piperidinols as novel H3 antagonists.EBI Athersys Inc.
20812727 157 Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomography.EBI National Institute of Mental Health
20801030 106 Discovery of potent and selective histamine H3 receptor inverse agonists based on the 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one scaffold.EBI F Hoffmann-La Roche Ltd
20685118 97 The synthesis and structure-activity relationship of 4-benzimidazolyl-piperidinylcarbonyl-piperidine analogs as histamine H3 antagonists.EBI Merck Research Laboratories
20667729 86 Discovery of substituted benzyl tetrazoles as histamine H3 receptor antagonists.EBI Evotec (UK) Ltd
20457525 225 In vitro studies on a class of quinoline containing histamine H3 antagonists.EBI Abbott Laboratories
20382018 81 Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists.EBI Johnson& Johnson Pharmaceutical Research& Development L.L.C.
19846299 52 Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.EBI Jagiellonian University Medical College
20042333 21 Benzimidazole- and indole-substituted 1,3'-bipyrrolidine benzamides as histamine H3 receptor antagonists.EBI Wyeth Research
19773164 53 Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl)thiazolopyridine as H3 receptor antagonists.EBI Schering-Plough Research Institute
19722526 30 Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity.EBI Arena Pharmaceuticals
19520574 49 Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.EBI Tsukuba Research Institute
19553110 16 Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.EBI Tsukuba Research Institute
19588934 71 Design of a new histamine H3 receptor antagonist chemotype: (3aR,6aR)-5-alkyl-1-aryl-octahydropyrrolo[3,4-b]pyrroles, synthesis, and structure-activity relationships.EBI Abbott Laboratories
18922693 37 2-Aryloxymethylmorpholine histamine H(3) antagonists.EBI Johnson& Johnson Pharmaceutical Research& Development L.L.C.
8158162 2 Verongamine, a Novel Bromotyrosine-Derived Histamine H3-Antagonist from the Marine Sponge Verongula giganteaEBI TBA
 21 Unsymmetrically substituted guanidines as potent histamine H3-receptor antagonistsEBI TBA
 7 Imetit and N-methyl derivatives. The transition from potent agonist to antagonist at histamine H3 receptors.1EBI TBA
 2 Two novel, potent and selective histamine H3 receptor agonistsEBI TBA
19119007 34 Novel imidazole-based histamine H3 antagonists.EBI Johnson & Johnson Pharmaceutical Research & Development
18841880 82 Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists.EBI Tsukuba Research Institute
18800848 8 Total synthesis and biological evaluation of the marine bromopyrrole alkaloid dispyrin: elucidation of discrete molecular targets with therapeutic potential.EBI Vanderbilt University
18752952 31 Benzimidazole-substituted (3-phenoxypropyl)amines as histamine H3 receptor ligands.EBI The Schering Plough Research Institute
18598020 75 Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.EBI Tsukuba Research Institute
18554904 26 Novel H3 receptor antagonists with improved pharmacokinetic profiles.EBI Arena Pharmaceuticals
18353639 27 Diamine derivatives containing imidazolidinylidene propanedinitrile as a new class of histamine H3 receptor antagonists. Part I.EBI Kyowa Hakko Kogyo Co. Ltd
17918921 35 Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.EBI Abbott Laboratories
17498953 17 A new class of histamine H3 receptor antagonists derived from ligand based design.EBI F. Hoffmann-La Roche Ltd
17169555 46 4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration.EBI Abbott Laboratories
16677814 67 Synthesis and SAR of novel histamine H3 receptor antagonists.EBI Lilly Research Laboratories
16300945 21 Aplysamine-1 and related analogs as histamine H3 receptor antagonists.EBI Johnson & Johnson Pharmaceutical Research and Development
16297617 87 Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists.EBI The Schering Plough Research Institute
16246552 57 Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.EBI The Schering Plough Research Institute
16190774 60 Synthesis and SAR of 5-amino- and 5-(aminomethyl)benzofuran histamine H3 receptor antagonists with improved potency.EBI Abbott Laboratories
15163206 18 Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.EBI University College London
15115409 72 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.EBI Freie Universität Berlin
14741270 152 A new class of potent non-imidazole H(3) antagonists: 2-aminoethylbenzofurans.EBI Abbott Laboratories
14741266 203 Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 3: 5-Substituted 3-phenyl-1,2,4-oxadiazoles as potent antagonists.EBI Abbott Laboratories
12798320 64 A new class of histamine H(3)-receptor antagonists: synthesis and structure-activity relationships of 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolines.EBI Abbott Laboratories
12781173 28 Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine.EBI The Schering-Plough Research Institute
12723960 58 Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.EBI Hokkaido University
12392739 41 Novel human histamine H(3) receptor antagonists.EBI Johnson and Johnson Pharmaceutical Research and Development
12372500 108 Synthesis and evaluation of potent pyrrolidine H(3) antagonists.EBI Abbott Laboratories
11958998 22 Identification of a novel, orally bioavailable histamine H(3) receptor antagonist based on the 4-benzyl-(1H-imidazol-4-yl) template.EBI The Schering Plough Research Institute
11855993 91 Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity.EBI Freie Universität Berlin
11294398 26 Different antagonist binding properties of human and rat histamine H3 receptors.EBI Freie Universität Berlin
11055360 13 Analogues and derivatives of ciproxifan, a novel prototype for generating potent histamine H3-receptor antagonists.EBI Freie Universität Berlin
10966752 60 New histamine H(3)-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency.EBI Freie Universität Berlin
10882362 2 Design, synthesis, and structure-activity relationships of novel non-imidazole histamine H(3) receptor antagonists.EBI The James Black Foundation
10514298 15 Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity.EBI Freie Universität Berlin
10072687 18 Design, synthesis, and structure-activity relationships of acetylene-based histamine H3 receptor antagonists.EBI Gliatech Inc.
10052966 30 Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity.EBI Freie Universität Berlin
9873525 13 4-[(1H-imidazol-4-yl) methyl] benzamidines and benzylamidines: novel antagonists of the histamine H3 receptor.EBI Schering-Plough Research Institute
9873505 50 Novel H3 receptor antagonists. Sulfonamide homologs of histamine.EBI Schering-Plough Research Institute
9873477 8 General construction pattern of histamine H3-receptor antagonists: change of a paradigm.EBI Freie Universität Berlin
9871722 14 New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine.EBI Gliatech Inc.
9871662 15 Trans-4-methyl-3-imidazoyl pyrrolidine as a potent, highly selective histamine H3 receptor agonist in vivo.EBI Schering-Plough Research Institute
9767653 7 4-Alkynylphenyl imidazolylpropyl ethers as selective histamine H3-receptor antagonists with high oral central nervous system activity.EBI Freie Universität Berlin
8809168 31 A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.EBI University College London
8676353 140 Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity.EBI Freie Universität Berlin
8632428 63 [125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor.EBI Freie Universität Berlin
8246239 84 Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives.EBI Solvay Duphar B.V.
7752184 12 A novel pyrrolidine analog of histamine as a potent, highly selective histamine H3 receptor agonist.EBI Schering-Plough Research Institute
7650687 22 Design of potent non-thiourea H3-receptor histamine antagonists.EBI University College London
1967317 11 Histamine H3 ligands: just pharmacological tools or potential therapeutic agents?EBI Vrije Universiteit
16915381 31 WAY-100635 is a potent dopamine D4 receptor agonist.BDB Purdue University
15608078 35 Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties.BDB Abbott Laboratories
12784105 53 Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.BDB Case Western Reserve University
12606603 59 Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.BDB Abbott Laboratories
2848779 9 Highly potent and selective ligands for a new class H3 of histamine receptor.BDB Unité 109
1321744 14 Multiple histamine receptors: properties and functional characteristics.BDB Queen's Medical Centre
18683917 57 The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.BDB Abbott Laboratories
18811133 12 Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.BDB Abbott Laboratories
18983139 12 cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), A New Histamine H4R Antagonist that Blocks Pain Responses against Carrageenan-Induced Hyperalgesia.BDB Abbott Laboratories
14722321 9 A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.BDB Johnson & Johnson Pharmaceutical