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48 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
12639549 2 Inhibition of inosine monophosphate dehydrogenase (IMPDH) by 2-[2-(Z)-fluorovinyl]inosine 5'-monophosphate.EBI The University of Georgia
12729643 31 Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening.EBI Roche Discovery Welwyn
24900625 52 Design and Discovery of 2-Arylquinazolin-4-ones as Potent and Selective Inhibitors of Tankyrases.EBI University of Bath
23668331 120 Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.EBI Brandeis University
20650640 24 Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure.EBI University of Minnesota
6142953 5 Inhibitors of inosinic acid dehydrogenase. 2-Substituted inosinic acids.EBI TBA
22950983 81 Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.EBI Brandeis University
22464133 5 Penicacids A-C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07.EBI Chinese Academy of Sciences
22310229 102 Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH.EBI Brandeis University
19624136 48 Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.EBI Brandeis University
11806722 14 Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.EBI Pharmasset Inc.
12014950 24 Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.EBI TBA
9484510 3 Synthesis of a methylenebis(phosphonate) analogue of mycophenolic adenine dinucleotide: a glucuronidation-resistant MAD analogue of NAD.EBI Codon Pharmaceuticals, Inc.
9572896 20 Isosteric analogues of nicotinamide adenine dinucleotide derived from furanfurin, thiophenfurin, and selenophenfurin as mammalian inosine monophosphate dehydrogenase (type I and II) inhibitors.EBI Universit£ di Camerino
9258359 9 Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity.EBI Codon Pharmaceuticals, Inc.
9016322 10 Rationally designed inhibitors of inosine monophosphate dehydrogenase.EBI University of Chicago
22172700 6 The design, synthesis and in vitro immunosuppressive evaluation of novel isobenzofuran derivatives.EBI Shenyang Pharmaceutical University
21924610 3 Aminothiazoles as¿-secretase modulators.EBI F. Hoffmann-La Roche Ltd
21324702 40 Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain.EBI University of Minnesota
20934342 14 Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives.EBI Hokkaido University
20491506 8 Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis.EBI University of Minnesota
18809333 14 Mycophenolic acid analogs with a modified metabolic profile.EBI University of Minnesota
18583139 26 Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase.EBI University of Minnesota
18038969 14 Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment.EBI University of Minnesota
17395461 2 Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor.EBI University of Minnesota
16884314 4 Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase.EBI University of Minnesota
16621550 27 Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.EBI Gilead Sciences, Inc.
16483773 24 Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.EBI UCB Celltech
16483769 15 Low molecular weight indole fragments as IMPDH inhibitors.EBI UCB Celltech
16202581 21 Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.EBI UCB Celltech
15664851 14 Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.EBI Celltech R and D
14505670 36 3-cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12781195 49 Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-Methoxy-4-(5-oxazolyl)phenyl moiety.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12657279 25 Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12657262 14 Novel indole-based inhibitors of IMPDH: introduction of hydrogen bond acceptors at indole C-3.EBI Bristol-Myers Squibb PRI
12565969 36 Quinolone-based IMPDH inhibitors: introduction of basic residues on ring D and SAR of the corresponding mono, di and benzofused analogues.EBI Bristol-Myers Squibb PRI
12565968 40 Novel inhibitors of IMPDH: a highly potent and selective quinolone-based series.EBI Bristol-Myers Squibb PRI
12392738 15 The TosMIC approach to 3-(oxazol-5-yl) indoles: application to the synthesis of indole-based IMPDH inhibitors.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12372516 14 A survey of cyclic replacements for the central diamide moiety of inhibitors of inosine monophosphate dehydrogenase.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12270177 23 Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12270168 40 Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase.EBI Bristol-Myers Squibb PRI
12127522 30 Rapid synthesis of triazine inhibitors of inosine monophosphate dehydrogenase.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
11965381 22 Novel diamide-based inhibitors of IMPDH.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
8863796 65 Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid.EBI Syntex Research
23663081 49 Design, synthesis and biological evaluation of novel inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitors.BDB Nycomed
18215774 12 Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis.BDB Brandeis University
17585753 26 Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).BDB Bristol-Myers Squibb Company
17958343 28 Probing Binding Requirements of Type I and Type II Isoforms of Inosine Monophosphate Dehydrogenase with Adenine-Modified Nicotinamide Adenine Dinucleotide Analogues.BDB University of Minnesota at Twin Citiies