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77 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28131094 66 New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation.EBI Universit£ de Lille
8411005 42 2-Amido-8-methoxytetralins: a series of nonindolic melatonin-like agents.EBI University of Groningen
1315395 18 Novel naphthalenic ligands with high affinity for the melatonin receptor.EBI Universite de Lille
27876250 60 Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CHEBI Jagiellonian University Medical College
26988801 55 Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.EBI Jagiellonian University Medical College
26390077 42 Tactical Approaches to Interconverting GPCR Agonists and Antagonists.EBI University of Minnesota
26820449 84 Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives.EBI Universit£ de Lille
26785296 32 Synthesis of 2-arylfuro[3,2-b]pyridines: Effect of the C2-aryl group on melatoninergic activity.EBI Universit£ d'Orl£ans
26367450 4 New coumarin-based fluorescent melatonin ligands. Design, synthesis and pharmacological characterization.EBI IQM-CSIC
26334942 43 Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines.EBI Universit£ degli Studi di Urbino"Carlo Bo"
26023814 79 Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential.EBI IQM-CSIC
24930835 18 Synthesis of new melatoninergic hexahydroindenopyridines.EBI Universidad de Valencia
25232966 52 Efficient synthesis of hexahydroindenopyridines and their potential as melatoninergic ligands.EBI Universidad de Valencia
24228714 64 MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.EBI The German University in Cairo
23228808 22 Development of substituted N-[3-(3-methoxylphenyl)propyl] amides as MT(2)-selective melatonin agonists: improving metabolic stability.EBI Hong Kong University of Science and Technology
23265885 30 Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors.EBI Universit£ de Paris-Sud
21775151 22 Bivalent ligand approach on N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide: synthesis, binding affinity and intrinsic activity for MT(1) and MT(2) melatonin receptors.EBI Universit£ degli Studi di Urbino Carlo Bo
20674373 84 Design, synthesis, and pharmacological effects of structurally simple ligands for MT(1) and MT(2) melatonin receptors.EBI Universit£ degli Studi di Bari
17149869 1 Design and synthesis of N-(3,3-diphenylpropenyl)alkanamides as a novel class of high-affinity MT2-selective melatonin receptor ligands.EBI Universit£ degli Studi di Urbino Carlo Bo
9804685 142 Pharmacophoric search and 3D-QSAR comparative molecular field analysis studies on agonists of melatonin sheep receptors.EBI Universit£ d'Orl£ans
22465637 48 4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators.EBI Lundbeck Research USA, Inc.
21726069 98 Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.EBI University of Namur
20684563 176 Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential.EBI H. Lundbeck A/S
20444610 71 Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands.EBI Univ Lille Nord de France
11585444 295 From hit to lead. Analyzing structure-profile relationships.EBI F-59000 Lille
10737738 78 Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles.EBI King's College London
21764185 12 Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands.EBI Universit£ d'Orl£ans
21568291 30 Synthesis of a novel series of tricyclic dihydrofuran derivatives: discovery of 8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as melatonin receptor (MT1/MT2) ligands.EBI Takeda Pharmaceutical Company Limited
21392858 28 Preparation and pharmacological evaluation of a novel series of 2-(phenylthio)benzo[b]thiophenes as selective MT2 receptor ligands.EBI Universit£ Lille Nord de France
21473625 42 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT2-selective agonists.EBI Takeda Pharmaceutical Company Limited
21377769 30 Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3.EBI Univ Lille Nord de France
21420861 50 Design and synthesis of 1-(2-alkanamidoethyl)-6-methoxy-7-azaindole derivatives as potent melatonin agonists.EBI Universit£ d'Orl£ans
20621473 56 Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.EBI Merck Research Laboratories
20591666 66 A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.EBI Università degli Studi di Milano
20227878 40 Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT(2)-selective melatonin ligands.EBI Hong Kong University of Science and Technology
19473848 7 Synthesis and pharmacological evaluation of 1,2,3,4-tetrahydropyrazino[1,2-a]indole and 2-[(phenylmethylamino)methyl]-1H-indole analogues as novel melatoninergic ligands.EBI University of W£rzburg
 26 The development of a charged melatonin receptor ligandEBI TBA
 12 Synthesis and receptor binding studies of quinolinic derivatives as melatonin receptor ligandsEBI TBA
19193160 42 2-[(2,3-dihydro-1H-indol-1-yl)methyl]melatonin analogues: a novel class of MT2-selective melatonin receptor antagonists.EBI University of Würzburg
18778943 53 Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands.EBI University of Lille 2
18657980 14 Synthesis and pharmacological evaluation of pentacyclic 6a,7-dihydrodiindole and 2,3-dihydrodiindole derivatives as novel melatoninergic ligands.EBI University of Würzburg
18372181 32 Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3.EBI Université de Lille
17481904 24 Synthesis and biological activity of new melatonin dimeric derivatives.EBI Università degli Studi di Urbino Carlo Bo
16759094 70 Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines.EBI University of Athens
15713384 28 (R)-2-(4-Phenylbutyl)dihydrobenzofuran derivatives as melatoninergic agents.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
15501061 51 Tetrahydroisoquinoline derivatives as melatonin MT2 receptor antagonists.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
15380218 40 N-[2-[2-(4-Phenylbutyl)benzofuran-4-yl]cyclopropylmethyl]acetamide: an orally bioavailable melatonin receptor agonist.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
15203165 80 Synthesis and structure-activity relationship of novel benzoxazole derivatives as melatonin receptor agonists.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
15013015 76 4-Substituted anilides as selective melatonin MT2 receptor agonists.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
14980664 48 Design and synthesis of benzoxazole derivatives as novel melatoninergic ligands.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
14643330 40 Heterocyclic aminopyrrolidine derivatives as melatoninergic agents.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12646022 22 Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands.EBI Université de Lille 2
12643943 43 Indanyl piperazines as melatonergic MT2 selective agents.EBI Bristol-Myers Squibb Pharmaceutical Research Institute
12213063 4 Synthesis of a novel series of tricyclic indan derivatives as melatonin receptor agonists.EBI Takeda Chemical Industries, Ltd.
12213062 70 Synthesis of a novel series of benzocycloalkene derivatives as melatonin receptor agonists.EBI Takeda Chemical Industries, Ltd.
12061881 94 Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands.EBI Institut de Chimie Pharmaceutique Albert Lespagnol
11960497 36 Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3).EBI Institut de Chimie Pharmaceutique Albert Lespagnol
11063602 84 Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors.EBI Université de Paris-Sud
9873728 19 Synthesis of benzocycloalkane derivatives as new conformationally restricted ligands for melatonin receptors.EBI Université de Paris-Sud
9435890 7 Development of a high-affinity ligand that binds irreversibly to Mel1b melatonin receptors.EBI Duquesne University
15131245 86 SR147778 [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of the CB1 cannabinoid receptor: biochemical and pharmacological characterization.BDB Sanofi-Synthelabo Recherche
12431845 84 Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder.BDB Lilly Research Laboratories
10455277 9 Ligand efficacy and potency at recombinant human MT2 melatonin receptors: evidence for agonist activity of some mt1-antagonists.BDB Universit&agrove; degli Studi di Milano
9840420 39 Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores.BDB King's College London
9733487 18 2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists.BDB Universita degli Studi di Milano
9647472 5 Pharmacological characterization of the human melatonin Mel1a receptor following stable transfection into NIH3T3 cells.BDB Universit&aagrove; degli Studi di Milano
9618903 37 Melatonin receptor pharmacology: toward subtype specificity.BDB King's College
9618428 39 GR196429: a nonindolic agonist at high-affinity melatonin receptors.BDB Glaxo Wellcome Research and Development, Ltd.
9089668 95 Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.BDB Northwestern University
8564266 77 Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed.BDB Vrije Universiteit
8161940 9 Melatonin receptors: localization, molecular pharmacology and physiological significance.BDB Rowett Research Institute
7946354 11 Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses.BDB Massachusetts General Hospital
7568007 15 Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor.BDB Massachusetts General Hospital