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TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211457(3-(2-((R)-1-(4-sec-butylfuran-2-yl)propylamino)-3,...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211449((R)-3-(3,4-dioxo-2-(1-(4-(pentan-3-yl)furan-2-yl)p...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236065((R)-3-(2-(1-(3-fluoro-5-methylphenyl)-2-methylprop...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211454((R)-3-(2-(1-(4-ethylfuran-2-yl)propylamino)-3,4-di...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211458((R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)propy...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236057((R)-3-(2-(1-(3-fluoro-4-methoxyphenyl)-2-methylpro...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236066((R)-3-(2-(1-(3,5-difluorophenyl)propylamino)-3,4-d...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236050((R)-3-(2-(1-(3-cyano-5-fluorophenyl)propylamino)-3...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236068((R)-3-(2-(1-(3-cyano-5-methylphenyl)propylamino)-3...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236064((R)-3-(2-(1-(3,5-difluorophenyl)-2-methylpropylami...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248279((S)-3-(3,4-dioxo-2-(2,2,2-trifluoro-1-(furan-2-yl)...)
Affinity DataKi:  2nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211453((R)-3-(2-(1-(4-butylfuran-2-yl)propylamino)-3,4-di...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211456((R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)ethyl...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248403((S)-3-(2-(2,2-difluoro-1-(4-isopropylfuran-2-yl)pr...)
Affinity DataKi:  2nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227000(3-[4-((R)-1-furan-2-yl-2,2-dimethyl-propylamino)-1...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227005(3-{4-[(R)-1-(4,5-dimethyl-furan-2-yl)-2-methyl-pro...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236059((R)-3-(2-(1-(3-fluoro-5-methylphenyl)propylamino)-...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211450((R)-3-(2-(1-(4-cyclopentylfuran-2-yl)propylamino)-...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211462((R)-3-(2-(cyclopropyl(4-isopropylfuran-2-yl)methyl...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297764((R)-5-cyano-3-(3,4-dioxo-2-(1-phenylpropylamino)cy...)
Affinity DataKi:  3nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50226999(2-hydroxy-N,N-dimethyl-3-{4-[(R)-1-(5-methyl-furan...)
Affinity DataKi:  3nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataKi:  4nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211464((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylfuran-...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50226995(3-[4-((R)-2,2-dimethyl-1-phenyl-propylamino)-1-oxo...)
Affinity DataKi:  4nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248456((S)-3-(3,4-dioxo-2-(2,2,3,3,3-pentafluoro-1-(5-met...)
Affinity DataKi:  4nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200880((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-...)
Affinity DataKi:  4nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211452((R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2-me...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297761((R)-6-bromo-3-(3,4-dioxo-2-(1-phenylpropylamino)cy...)
Affinity DataKi:  4nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211455((R)-3-(2-(1-(4-tert-butylfuran-2-yl)propylamino)-3...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211459((R)-3-(2-(1-(4-cyclohexylfuran-2-yl)propylamino)-3...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248336(3-(2-((1S,2S)-2-fluoro-1-(4-methylfuran-2-yl)propy...)
Affinity DataKi:  4nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211448((R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2,2-...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50432427(CHEMBL2349306)
Affinity DataKi:  4.10nMAssay Description:Displacement of [125I]-IL8 from human CXCR2 transfected in HEK293 cells after 4 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataKi:  4.40nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236062((R)-2-hydroxy-N,N-dimethyl-3-(2-(2-methyl-1-(3-met...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297740((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataKi:  4.5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236052((R)-3-(2-(cyclopropyl(3,5-difluorophenyl)methylami...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227003(3-[4-((R)-1-benzo[1,3]dioxol-5-yl-2,2-dimethyl-pro...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297741((R)-5-cyano-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propy...)
Affinity DataKi:  5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200887((R)-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propylamino)c...)
Affinity DataKi:  5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297738((R)-1-(3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobu...)
Affinity DataKi:  5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248453((S)-3-(2-(2,2-difluoro-1-(5-methylfuran-2-yl)butyl...)
Affinity DataKi:  5nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227001(3-{4-[(R)-2,2-dimethyl-1-(5-methyl-furan-2-yl)-pro...)
Affinity DataKi:  5nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50226996(2-hydroxy-N,N-dimethyl-3-[1-oxo-4-((R)-1-phenyl-pr...)
Affinity DataKi:  5nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200877((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylthioph...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50211451((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(4-methylthioph...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200880((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248545((S)-3-(2-(1-(benzo[d][1,3]dioxol-5-yl)-2,2,2-trifl...)
Affinity DataKi:  5nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248502((S)-3-(2-(1-(4-chlorofuran-2-yl)-2,2,2-trifluoroet...)
Affinity DataKi:  5nMAssay Description:Binding affinity to CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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