BDBM50221063 (1S,2S,12bS,12cS)-1,2-Diol-2,4,5,7, 12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1-acetate::1-Acetoxylycorine::1-Acetyllycorine::1-O-Acetyllycorine::CHEMBL251077::acetic acid (1S,2S,12bS,12cS)-2-hydroxy-1,2,4,5,12b,12c-hexahydro-7H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-1-yl ester

SMILES CC(=O)O[C@@H]1[C@@H](O)C=C2CCN3Cc4cc5OCOc5cc4[C@H]1[C@@H]23

InChI Key InChIKey=BIGUPJIJZYZJMV-VIBAHUMZSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221063   

TargetAcetylcholinesterase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50221063((1S,2S,12bS,12cS)-1,2-Diol-2,4,5,7, 12b,12c-hexahy...)
Affinity DataKi:  430nMAssay Description:Inhibition of AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50221063((1S,2S,12bS,12cS)-1,2-Diol-2,4,5,7, 12b,12c-hexahy...)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of human CYP3A4 assessed as biotransformation of 7-benzyloxyquinolineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50221063((1S,2S,12bS,12cS)-1,2-Diol-2,4,5,7, 12b,12c-hexahy...)
Affinity DataIC50:  960nMAssay Description:Inhibition of AChE by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed