BDBM50191599 3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4-one::3-(imidazolylmethyl)flavone::CHEMBL213587

SMILES O=c1c(Cn2ccnc2)c(oc2ccccc12)-c1ccccc1

InChI Key InChIKey=CAKKGEJFZFTSEV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50191599   

TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50191599(3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...)
Affinity DataIC50:  71nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50191599(3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...)
Affinity DataIC50:  71nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50191599(3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50191599(3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50191599(3-((1H-imidazol-1-yl)methyl)-2-phenyl-4H-chromen-4...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed