BDBM50296860 6-Methoxyflavanone::6-methoxy-2-phenylchroman-4-one::CHEMBL476292::NSC-50184

SMILES COc1ccc2OC(CC(=O)c2c1)c1ccccc1

InChI Key InChIKey=YURQMHCZHLMHIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296860   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50296860(6-Methoxyflavanone | 6-methoxy-2-phenylchroman-4-o...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50296860(6-Methoxyflavanone | 6-methoxy-2-phenylchroman-4-o...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of MDR1 expressed in MDCK cells using rhodamine 123 staining by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50296860(6-Methoxyflavanone | 6-methoxy-2-phenylchroman-4-o...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Meijo University

Curated by ChEMBL
LigandPNGBDBM50296860(6-Methoxyflavanone | 6-methoxy-2-phenylchroman-4-o...)
Affinity DataIC50:  3.95E+4nMAssay Description:Antagonist activity at androgen receptor in human MDA-kb2 cells assessed as inhibition of DHT-induced luciferase activity by luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed