BDBM50312648 (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one::(S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychroman-4-one::5,4'-dihydroxy-7-methoxyflavanone::7-O-methylnaringenin::CHEMBL448297::Sakuranetin

SMILES COc1cc(O)c2C(=O)C[C@H](Oc2c1)c1ccc(O)cc1

InChI Key InChIKey=DJOJDHGQRNZXQQ-AWEZNQCLSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312648   

TargetSialidase-2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50312648((2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-d...)
Affinity DataIC50:  8.90E+5nMAssay Description:Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 31(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50312648((2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-d...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50312648((2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-d...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reagent methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed