BDBM50010912 CHEMBL721::acrolein::acrylaldehyde

SMILES C=CC=O

InChI Key InChIKey=HGINCPLSRVDWNT-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50010912   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010912(CHEMBL721 | acrolein | acrylaldehyde)
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of TRPA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010912(CHEMBL721 | acrolein | acrylaldehyde)
Affinity DataEC50:  800nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010912(CHEMBL721 | acrolein | acrylaldehyde)
Affinity DataEC50:  2.69E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010912(CHEMBL721 | acrolein | acrylaldehyde)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010912(CHEMBL721 | acrolein | acrylaldehyde)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human TRPA1 expressed in Xenopus oocytes assessed as increase in calcium influx by two electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50010912(CHEMBL721 | acrolein | acrylaldehyde)
Affinity DataIC50:  5.25E+4nMAssay Description:Inhibition of [3H]dopamine uptake at DAT in rat brain striatal synaptosomes by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed