BDBM50177729 Aplysamine-1::CHEMBL380697::aplysamine

SMILES CN(C)CCCOc1c(Br)cc(CCN(C)C)cc1Br

InChI Key InChIKey=LWENJEAGCYZOBC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177729   

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50177729(Aplysamine-1 | CHEMBL380697 | aplysamine)
Affinity DataKi:  30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50177729(Aplysamine-1 | CHEMBL380697 | aplysamine)
Affinity DataKi:  30nMAssay Description:Inhibition of histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50177729(Aplysamine-1 | CHEMBL380697 | aplysamine)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50177729(Aplysamine-1 | CHEMBL380697 | aplysamine)
Affinity DataKi:  249nMAssay Description:Displacement of N-[3H]methylhistamine from rat histamine H3 receptor in rat cortical hemispheresMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed