BDBM22888 1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea::Burimamide::CHEMBL12160
SMILES CNC(=S)NCCCCc1cnc[nH]1
InChI Key InChIKey=HXRBAVXGYZUSED-UHFFFAOYSA-N
Data 17 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 22888
Affinity DataKi: 13nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH3R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Binding affinity to the human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity to the human histamine H4 receptorMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database