BDBM18364 (2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidine-3,4,5-triol::CN-DNJ::US9181184, 32::alpha-1-C-Nonyl-DNJ

SMILES CCCCCCCCC[C@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=PMSTUSHNMMAWCI-UXXRCYHCSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18364   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18364((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...)
Affinity DataKi:  200nM ΔG°:  -9.50kcal/mole IC50:  270nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM18364((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...)
Affinity DataEC50:  7.00E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18364((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...)
Affinity DataIC50:  4.80E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed