BDBM50226664 2-hydroxy-3,9,10-trimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium::CHEMBL400345::columbamine
SMILES COc1cc2CC[n+]3cc4c(OC)c(OC)ccc4cc3-c2cc1O
InChI Key InChIKey=YYFOFDHQVIODOQ-UHFFFAOYSA-O
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50226664
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Hangzhou Normal University
Curated by ChEMBL
Hangzhou Normal University
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant KDM1A (unknown origin) expressed in Escherichia coli BL21 using H3K4Me2 peptide as substrate preincubated for 10 mins follo...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Hangzhou Normal University
Curated by ChEMBL
Hangzhou Normal University
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 using H3K4me2 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+5nMAssay Description:Inhibition of Human immunodeficiency virus 1 NL4.3 reverse transcriptase activityMore data for this Ligand-Target Pair