BDBM50085531 3,4',5-trihydroxybibenzyl::5-(4-hydroxyphenethyl)benzene-1,3-diol::5-[2-(4-Hydroxy-phenyl)-ethyl]-benzene-1,3-diol::5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol::CHEMBL111234::alpha,beta-dihydro-3,40,5-trihydroxystilbene::dihydroresveratrol

SMILES Oc1ccc(CCc2cc(O)cc(O)c2)cc1

InChI Key InChIKey=HITJFUSPLYBJPE-UHFFFAOYSA-N

Data  4 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085531   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50085531(3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...)
Affinity DataIC50:  2.47E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50085531(3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hyogo University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50085531(3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as induction of calcium influx at 30 uM after 6 mins by Fluo-4 dye-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hyogo University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50085531(3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx preincubated for 6 mins followed by AITC addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50085531(3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human aromatase using dibenzylfluorescein as substrate preincubated for 30 mins measured after 2 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed