BDBM50397204 ELINOGREL
SMILES CNc1cc2[nH]c(=O)n(-c3ccc(NC(=O)NS(=O)(=O)c4ccc(Cl)s4)cc3)c(=O)c2cc1F
InChI Key InChIKey=LGSDFTPAICUONK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50397204
Affinity DataKi: 23nMAssay Description:Displacement of [33P]2-MeS-ADP from human recombinant P2Y12 receptor expressed in CHO cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Binding affinity to P2Y12 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]2MeSADP from human P2Y12 preincubated for 5 mins followed by [3H]2MeSADP addition and measured after 15 mins by scintillation cou...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Displacement of [3H]-2-Mes-ADP from human P2Y12 receptor in platelets by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at P2Y12 receptor in human platelets assessed as inhibition of ADP-induced platelet aggregation by microplate reader analysisMore data for this Ligand-Target Pair