BDBM50006202 3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-(4-methoxy-phenyl)-ethyl]-3-methyl-butyramide::A-64662::CHEMBL300337::ENALKIREN
SMILES COc1ccc(C[C@H](NC(=O)CC(C)(C)N)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)[C@@H](O)CC(C)C)cc1
InChI Key InChIKey=KQXVERRYBYGQJZ-WRPDIKACSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50006202
Affinity DataIC50: 2.30nMpH: 7.7Assay Description:Inhibitory activity against renin in monkey plasma at pH 7.7More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.4Assay Description:Inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:In vitro inhibition of monkey renin.More data for this Ligand-Target Pair
TargetPepsin A(Porcine)
Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for the percent inhibition of pepsinMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.4Assay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
TargetCathepsin D(Bos taurus)
Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for the percent inhibition of Cathepsin D in BovineMore data for this Ligand-Target Pair
TargetCathepsin D(Bos taurus)
Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.
Curated by ChEMBL
Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair