BDBM50292475 CHEMBL510130::hypophyllanthin

SMILES COC[C@@H]1Cc2cc(OC)c3OCOc3c2[C@@H]([C@H]1COC)c1ccc(OC)c(OC)c1

InChI Key InChIKey=LBJCUHLNHSKZBW-XGHQBKJUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292475   

TargetEndothelin-1 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50292475(CHEMBL510130 | hypophyllanthin)
Affinity DataIC50:  5.80E+5nMAssay Description:Displacement of [125I]endothelin-1 from ETA receptor in rat A10 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292475(CHEMBL510130 | hypophyllanthin)
Affinity DataIC50: >5.00E+5nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292475(CHEMBL510130 | hypophyllanthin)
Affinity DataIC50:  4.00E+4nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article