BDBM50012894 CHEMBL292707::Ibuproxam::N-Hydroxy-2-(4-isobutyl-phenyl)-propionamide::N-hydroxy-2-(4-isobutylphenyl)propanamide

SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)NO

InChI Key InChIKey=BYPIURIATSUHDW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50012894   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012894(CHEMBL292707 | Ibuproxam | N-Hydroxy-2-(4-isobutyl...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012894(CHEMBL292707 | Ibuproxam | N-Hydroxy-2-(4-isobutyl...)
Affinity DataIC50:  4.84E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012894(CHEMBL292707 | Ibuproxam | N-Hydroxy-2-(4-isobutyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012894(CHEMBL292707 | Ibuproxam | N-Hydroxy-2-(4-isobutyl...)
Affinity DataIC50:  5.70E+3nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012894(CHEMBL292707 | Ibuproxam | N-Hydroxy-2-(4-isobutyl...)
Affinity DataIC50:  4.57E+4nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed