BDBM29136 CHEMBL92401::Euphozid::Iprazid::Iproniazid
SMILES CC(C)NNC(=O)c1ccncc1
InChI Key InChIKey=NYMGNSNKLVNMIA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 156 hits for monomerid = 29136
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
Affinity DataIC50: 6.56E+3nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
Affinity DataIC50: 4.32E+3nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+3nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
Affinity DataIC50: 6.61E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BT1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BT1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...More data for this Ligand-Target Pair
Affinity DataIC50: 7.01E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected insect cell microsomes assessed as p-tyramine conversion to resorufin and H2O...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cell microsomes assessed as p-tyramine conversion to resorufin and H2O...More data for this Ligand-Target Pair
Affinity DataIC50: 6.97E+3nMAssay Description:Inhibition of human recombinant MAO-A assessed as H2O2 production using p-tyramine substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.65E+3nMAssay Description:Inhibition of human recombinant MAO-B assessed as H2O2 production using p-tyramine substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate assessed as H2O2 production after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of human recombinant MAO-A using p-tyramine as substrate assessed as H2O2 production after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.48E+3nMAssay Description:Inhibition of human MAO-A using p-tyramine as substrate assessed as H2O2 production by amplex red assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate assessed as H2O2 production by amplex red assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOA by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAOB by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.57E+3nMAssay Description:Inhibition of human recombinant MAO-A using p-tyramine substrate after 15 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.97E+3nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine substrate after 15 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI cells using p-tyramine as substrate after 15 mins by Amplex Red-based flu...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI cells using p-tyramine as substrate after 15 mins by Amplex Red-based flu...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate assessed as reduc...More data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate assessed as reduc...More data for this Ligand-Target Pair
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate after 30 mins by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine as substrate after 30 mins by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in BTI cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54nMAssay Description:Inhibition of human recombinant MAOB expressed in BTI cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of MAOB in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorometryMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAO-A assessed as inhibition of production of hydrogen peroxide after 15 mins by Amplex Red fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAO-B assessed as inhibition of production of hydrogen peroxide after 15 mins by the Amplex Red fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human MAOA expressed in BTI insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human MAOB expressed in BTI insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human MAOA by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human MAOB by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI insect cells assessed as hydrogen peroxide production after 15 mins by Amp...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI insect cells assessed as hydrogen peroxide production after 15 mins by Amp...More data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair