BDBM19516 (2S)-N-[(3S,5E)-6-(benzenesulfonyl)-4-oxo-1-phenylhex-5-en-3-yl]-4-methyl-2-(morpholin-4-ylcarbonylamino)pentanamide::CHEMBL222649::LHVS::Morpholinurea-Leu-Hph-Vinyl-Sulfone-Phenyl::Morpholinurea-Leucine-Homophenylalaninevinyl Phenyl Sulfone
SMILES CC(C)C[C@@H](NC(=O)N1CCOCC1)C(=O)N[C@H](CCc1ccccc1)C=CS(=O)(=O)c1ccccc1
InChI Key InChIKey=YUMYYTORLYHUFW-AOYPEHQESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 19516
Affinity DataIC50: 1.20nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin C after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of proteinase-3 activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant cathepsin L after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin S after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of neutrophil elastase activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of cathepsin G activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of human recombinant cathepsin B after 10 minsMore data for this Ligand-Target Pair