BDBM50248158 CHEMBL450195::N-butylresorcinol::US8993596, 4-Butylresorcinol (Rucinol)::US9422261, 4-Butyl- resorcinol

SMILES CCCCc1ccc(O)cc1O

InChI Key InChIKey=CSHZYWUPJWVTMQ-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50248158   

TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  1.00E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  150nMAssay Description:Inhibition of mushroom tyrosinase activity after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5,6-dihydroxyindole-2-carboxylic acid oxidase(Mus musculus (Mouse))
Galderma Research & Development

US Patent
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  3.00E+3nMpH: 6.8 T: 2°CAssay Description:The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed