BDBM50220832 CHEMBL8211::N-ethylmaleimide
SMILES CCN1C(=O)C=CC1=O
InChI Key InChIKey=HDFGOPSGAURCEO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50220832
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
Ulsan National Institute of Science and Technology (UNIST)
Curated by ChEMBL
Ulsan National Institute of Science and Technology (UNIST)
Curated by ChEMBL
Affinity DataKi: 2.09E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+4nMAssay Description:Displacement of [3H]2-OG from human MGL by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of rat cerebellar membranes MAGL-like activity preincubated for 30 mins followed by 2-AG substrate addition after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+5nMpH: 7.5 T: 2°CAssay Description:Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Pittsburgh
Curated by ChEMBL
University Of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: 4.68E+4nMAssay Description:Inhibition of [3H]dopamine uptake at DAT in rat brain striatal synaptosomes by liquid scintillation counting analysisMore data for this Ligand-Target Pair