BDBM50240041 1-phenyl-2-thiourea::1-phenylthiourea::CHEMBL263376::N-Phenyl-thiourea::N-Phenylthiourea::phenylthiourea

SMILES NC(=S)Nc1ccccc1

InChI Key InChIKey=FULZLIGZKMKICU-UHFFFAOYSA-N

Data  2 KI  6 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240041   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataKi:  1.70E+3nMAssay Description:Uncompetitive inhibition of recombinant human tyrosinase expressed in baculovirus infected sf9 cells using L-DOPA as substrate by double-reciprocal p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuccinyl-diaminopimelate desuccinylase(Haemophilus influenzae)
Loyola University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Haemophilus influenzae recombinant DapEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of tyrosinase in alpha-MSH-induced mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate by spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed