BDBM50331544 7H-furo[3,2-g]chromen-7-one::CHEMBL164660::Furo[3,2-g]chromen-7-one::psoralen

SMILES O=c1ccc2cc3ccoc3cc2o1

InChI Key InChIKey=ZCCUUQDIBDJBTK-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50331544   

TargetCytochrome P450 2A6(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataKi:  600nMAssay Description:Mechanism based inhibition of human cytochrome P450 2A6 measured by coumarin 7-hydroxylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kinki University

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human BACE1 using Rh-EVNLDAEFK as substrate after 60 mins by fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Biopharmanet

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of NF-KB p50 subunit/DNA interaction after 20 mins by EMSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Monastir

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50:  6.48E+3nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) using acetylcholine iodide as substrate preincubated for 15 mins prior to substrate addition by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using benzylamine as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Gyeongsang National University

LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50: >1.50E+5nMpH: 8.0Assay Description:Reactions were performed in a total volume of 200 mL, which contained thefollowing components: 20mM Tris-buffer, pH 8.0, 10mM DTT, 30 mM Z-RLRGG-AMC,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50331544(7H-furo[3,2-g]chromen-7-one | CHEMBL164660 | Furo[...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed