BDBM329472 5-(6-ethylpyridin-3-yl)-4- (((1S,2S)-2-(5- methoxypyridin-2- yl)cyclopropyl)methoxy)- 2-methylpyrimidine::US9663513, 85
SMILES CCc1ccc(cn1)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc(OC)cn1
InChI Key InChIKey=JNJUTFFGOXSBRN-APWZRJJASA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 329472
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.860nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair