BDBM10073 (3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one::C-5 substituted oxindole inhibitor 4a

SMILES COc1cc[nH]c1\C=C1/C(=O)Nc2ccccc12

InChI Key InChIKey=VFRYWNKBMCTSEA-NTMALXAHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10073   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Hoffmann-La Roche

LigandPNGBDBM10073((3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-2,3...)
Affinity DataIC50:  5.36E+3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
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