BDBM10136 9-fluoro-7-methyl-5-(1H-pyrrol-2-yl)-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaen-3-one::trisubstituted naphthostyril analogue 4b

SMILES Cc1cc(-c2ccc[nH]2)c2C(=O)Nc3ccc(F)c1c23

InChI Key InChIKey=PHJMZSOICSKGSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10136   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Hoffmann-La Roche

LigandPNGBDBM10136(9-fluoro-7-methyl-5-(1H-pyrrol-2-yl)-2-azatricyclo...)
Affinity DataIC50:  376nMAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed