BDBM10213 5-({[5-(1-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}butyl)thiophen-2-yl]methyl}sulfamoyl)-2-hydroxybenzoic acid::sulfonamide analog 35

SMILES CCCC(C(=O)N[C@@H](CC(O)=O)C=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(c2)C(O)=O)s1

InChI Key InChIKey=DOXHHNBSNRBIQZ-SFVWDYPZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10213   

TargetCaspase-3(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM10213(5-({[5-(1-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbam...)
Affinity DataKi:  300nM ΔG°:  -8.89kcal/moleT: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed