BDBM102968 US8541427, 39 racemic
SMILES COc1nc(nc(C)c1F)N1C[C@H]2C(=O)N(C)C(N)=N[C@]2(C1)c1ccc(F)c(Cl)c1F
InChI Key InChIKey=ORQCMGPTGLLMAF-APBUJDDRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 102968
Affinity DataKi: 9.20nM ΔG°: -11.1kcal/mole IC50: 40nMT: 2°CAssay Description:A homogeneous time-resolved FRET assay was used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. The assay monit...More data for this Ligand-Target Pair