BDBM10379 4,7-dimethyl-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2(6),7,9,11-pentaene-3,5-dione::cid_706730::pyrrolo[3,4-c]quinoline 6e

SMILES CN1C(=O)c2c(C1=O)c1ccccc1nc2C

InChI Key InChIKey=ZFGLUIRRXJEQSV-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10379   

TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10379(4,7-dimethyl-4,8-diazatricyclo[7.4.0.0^{2,6}]tride...)
Affinity DataIC50:  6.36E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM10379(4,7-dimethyl-4,8-diazatricyclo[7.4.0.0^{2,6}]tride...)
Affinity DataEC50:  794nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM10379(4,7-dimethyl-4,8-diazatricyclo[7.4.0.0^{2,6}]tride...)
Affinity DataEC50:  1.84E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay