BDBM103839 Danoprevir

SMILES CC(C)(C)OC(=O)NC1CCCCC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C1=O)OC(=O)N1Cc2cccc(F)c2C1)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=ZVTDLPBHTSMEJZ-QIFYYAQYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103839   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University Of Massachusetts Medical School

LigandPNGBDBM103839(Danoprevir)
Affinity DataIC50:  0.240nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed