BDBM103867 US9695165, 50

SMILES CCN1C(=O)N(Cc2cnc(cc12)-c1ccc2OCCN(C(=O)C=C)c2c1)c1c(Cl)c(OC)cc(OC)c1Cl

InChI Key InChIKey=GTLGWOYTUWJOKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103867   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM103867(US9695165, 50)
Affinity DataIC50:  55nMAssay Description:MDA-MB453 cells were plated in 96-well cell culture plates at a density of 1x105 cells. Cells were allowed to attach, and growth media was replaced w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM103867(US9695165, 50)
Affinity DataIC50: <10nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In DepthDetails US Patent